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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the C-terminal region of human HSL.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0660
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
Q05469
- 抗体英文名:
Anti-HSL Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-HSL Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Hormone-sensitive lipase (HSL) is a crucial intracellular enzyme that regulates lipid metabolism by hydrolyzing stored fats into usable energy. Encoded by the LIPE gene, HSL is primarily active in adipose tissue, where it breaks down triglycerides into free fatty acids and glycerol during lipolysis. This process is hormonally regulated: catecholamines and adrenocorticotropic hormone (ACTH) activate HSL, while insulin inhibits it, balancing energy mobilization and storage. HSL is expressed in steroidogenic tissues like the testes, where it hydrolyzes cholesteryl esters to release free cholesterol, a precursor for steroid hormone synthesis. HSL's broad substrate specificity also includes diacylglycerols, monoacylglycerols, and retinyl esters, highlighting its versatile role in lipid homeostasis. Due to its central role in energy balance, HSL is a significant focus in research areas related to metabolic disorders, including obesity, insulin resistance, and type 2 diabetes.
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文献和实验该产品被引用文献
Greenberg, A.S. et al. (2001) J. Biol. Chem. 276, 45456-61.
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Anti-HSL Recombinant Rabbit Monoclonal Ab
¥860






