- ￥860
- Elucigen Biosciences
- ERB0586
- 2025年08月13日
- ICC, IHC
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide corresponding to the N-terminal region, extracellular domain of human CACNA2D1.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
ERB0586
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
Elucigen Biosciences
- 宿主：
Rabbit
- 应用范围：
ICC, IHC
- 浓度：
0.5 mg/mL
- 靶点：
P54289
- 抗体英文名：
Anti-CACNA2D1 Recombinant Rabbit Monoclonal Ab
- 抗体名：
Anti-CACNA2D1 Recombinant Rabbit Monoclonal Ab
- 规格：
25μg/100μg/500μg
| 规格： | 25μg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | 询价 |
| 规格： | 500μg | 产品价格： | 询价 |
The CACNA2D1 gene encodes the α2δ-1 subunit of voltage-dependent calcium channels, which are essential for the regulation of calcium ion influx into cells. This subunit plays a pivotal role in the modulation of calcium current density and the kinetics of channel activation and inactivation, thereby influencing processes such as excitation-contraction coupling in muscle cells and synaptic function in neurons. Beyond its structural and functional contributions to calcium channels, CACNA2D1 is implicated in various physiological and pathological conditions. Alterations in its expression have been associated with neuroinflammatory responses in stroke and may serve as a potential biomarker for disease severity. Additionally, research has identified a role for CACNA2D1 regulation in elevated intraocular pressure and glaucoma susceptibility. Understanding the multifaceted roles of CACNA2D1 enhances our comprehension of cellular excitability and holds promise for developing targeted therapeutic strategies for related disorders.
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文献和实验该产品被引用文献
Dahimene, S. et al. (2022) Brain. 145(8):2721-2729.
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Anti-CACNA2D1 Recombinant Rabbit Monoclonal Ab
￥860
