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Anti-VEGF Receptor 2 / VEGFR2

Recombinant Rabbit Monoclonal Ab
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  • ¥860
  • Elucigen Biosciences
  • ERB0533
  • 2025年08月13日
  • ICC, IHC, WB
  • Rabbit
  • Human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant protein corresponding to the C-terminal region of human VEGFR2.

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human

    • 保质期

      12 months from the shipping date of the product.

    • 抗原来源

      Human

    • 目录编号

      ERB0533

    • 级别

      Primary Antibodies

    • 库存

      Available

    • 供应商

      Elucigen Biosciences

    • 宿主

      Rabbit

    • 应用范围

      ICC, IHC, WB

    • 浓度

      0.5 mg/mL

    • 靶点

      P35968

    • 抗体英文名

      Anti-VEGF Receptor 2 / VEGFR2 Recombinant Rabbit Monoclonal Ab

    • 抗体名

      Anti-VEGF Receptor 2 / VEGFR2 Recombinant Rabbit Monoclonal Ab

    • 规格

      25μg/100μg/500μg

    规格:25μg产品价格:¥860.0
    规格:100μg产品价格:询价
    规格:500μg产品价格:询价
    VEGFR2 (Vascular Endothelial Growth Factor Receptor 2), also known as KDR (Kinase insert Domain Receptor), is a transmembrane receptor primarily expressed on the surface of endothelial cells. It plays a critical role in angiogenesis (the formation of new blood vessels) by mediating the effects of vascular endothelial growth factor (VEGF), particularly VEGF-A, on blood vessel formation. Upon VEGF binding, VEGFR2 undergoes dimerization and autophosphorylation, activating intracellular signaling pathways that promote endothelial cell proliferation, migration, and survival. These processes are essential for normal vascular development, wound healing, and tissue repair. VEGFR2 is also implicated in pathological conditions such as cancer, diabetic retinopathy, and vascular diseases, where abnormal VEGF signaling contributes to tumor growth and inflammatory responses.

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    图标文献和实验
    该产品被引用文献
    Meyer, M. et al. (1999) EMBO J 18, 363-74.
    相关实验
    • Indirect Immunofluorescence

      Reagents:  NGS-Normal Goat Serum  PBST-0.5% Tween-20/CMF-PBS  CMF-PBS  1°Ab-mouse MF20 (anti-myosin monoclonal)  1°Ab-rabbit myoD (anti-myoD polyclonal)  2°Ab-goat anti-mouse IgG-FITC  2°Ab-goat anti-rabbit IgG-FITC

    • ELISA PROTOCOL 【Yale University 】

      -nitrophenyl phosphate (5 mg/tablet). SigmaCat.# N93895) AP-conjugated secondary Ab: AP-Rabbit anti-mouse IgG(Zymed). Reconstitute in ddH2O as prescribed by manufacturer andaliquot and store at -70 °C.6) 100 mM EDTA pH

    • Staining for total receptors

      , and apply primary Ab only to the coverslip. Incubate 45'. Dilute antibody with Blotto. Some typical dilutions are listed below: monoclonal M1 mouse anti-Flag antibody (Sigma , Covance ) (Ca+2 sensitive) 1:350-1:500; polyclonal 12CA5 mouse anti-HA (Roche

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    文献支持
    Anti-VEGF Receptor 2 / VEGFR2 Recombinant Rabbit Monoclonal Ab
    ¥860