Anti-Caspase-8 Recombinant Rab

Caspase-8 is a key enzyme in the family of caspases, which are proteases involved in the regulation of programmed cell death, or apoptosis. Specifically, Caspase-8 plays a crucial role in the extrinsic apoptotic pathway, which is triggered by external signals such as the binding of death ligands (e.g., FasL or TNF-α) to their respective receptors on the cell surface. Upon activation, Caspase-8 initiates a cascade of proteolytic events that ultimately lead to cell death. In addition to its role in apoptosis, Caspase-8 is also involved in regulating other cellular processes, including necroptosis and immune responses, making it a critical player in maintaining cellular homeostasis and defense mechanisms.