Anti-METTL14 Recombinant Rabbi

Methyltransferase-like protein 14 (METTL14) is an essential enzyme that plays a critical role in RNA modification. It is part of the m6A methyltransferase complex, which is responsible for adding N6-methyladenosine (m6A), the most abundant internal modification on messenger RNA (mRNA), to specific sites within RNA molecules. METTL14 works in concert with other components of the methyltransferase complex, such as METTL3, to regulate the m6A modification on RNA. This modification influences various aspects of RNA metabolism, including splicing, stability, transport, and translation, and plays a significant role in controlling gene expression at the post-transcriptional level. METTL14 has been implicated in cellular processes such as development, differentiation, and immune response. It has also been shown to play a role in cancer biology, with dysregulation of m6A methylation contributing to tumorigenesis, metastasis, and chemoresistance. Given its crucial role in RNA regulation, METTL14 is a key player in both normal cellular function and disease progression, making it an important target for research into therapeutic applications.