Anti-OGT Recombinant Rabbit Mo

O-linked N-acetylglucosamine transferase (OGT), also known as the 110 kDa subunit of OGT, is a glycosyltransferase enzyme that catalyzes the addition of O-linked N-acetylglucosamine (O-GlcNAc) to serine and threonine residues on nuclear and cytoplasmic proteins. This post-translational modification, known as O-GlcNAcylation, regulates various cellular processes, including signal transduction, transcription, protein stability, and cell cycle progression. OGT is essential for maintaining cellular homeostasis and plays a critical role in metabolic sensing, stress response, and epigenetic regulation. The enzyme is involved in diverse biological functions, from neuronal development to immune response and cancer progression. OGT dysregulation has been implicated in a variety of diseases, including neurodegenerative disorders, diabetes, and cancer.