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- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the C-terminal region of human Rac1.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse (predicted), Rat (predicted)
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0652
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC
- 浓度:
0.5 mg/mL
- 靶点:
P63000
- 抗体英文名:
Anti-Rac1 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-Rac1 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Rac1 (Ras-related C3 botulinum toxin substrate 1) is a small (~21 kDa) signaling GTPase belonging to the Rho family of GTPases. It functions as a molecular switch cycling between an active GTP-bound state and an inactive GDP-bound state, regulating diverse cellular processes. Rac1 plays a pivotal role in actin cytoskeleton organization, influencing cell morphology, motility, and adhesion. It is involved in the formation of lamellipodia, membrane ruffles, and cell migration. Additionally, Rac1 participates in cell cycle progression, transcriptional regulation, and reactive oxygen species production. Dysregulation of Rac1 activity has been implicated in various pathological conditions, including cancer progression, neurodevelopmental disorders, and insulin resistance. Due to its central role in multiple signaling pathways, Rac1 is considered a potential therapeutic target in several diseases.
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文献和实验该产品被引用文献
Bernards, A. and Settleman, J. (2004) Trends Cell Biol 14, 377-85.
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Anti-Rac1 Recombinant Rabbit Monoclonal Ab
¥860






