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Anti-Phospho-Cofilin (Ser3) Re

combinant Rabbit Monoclonal Ab
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  • ¥860
  • Elucigen Biosciences
  • ERB0647
  • 2025年08月13日
  • ICC, WB
  • Rabbit
  • Human, Mouse (predicted), Rat (predicted)
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthetic peptide corresponding to the amino acids surrounding phosphoserine 3 in human Cofilin.

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human, Mouse (predicted), Rat (predicted)

    • 保质期

      12 months from the shipping date of the product.

    • 抗原来源

      Human

    • 目录编号

      ERB0647

    • 级别

      Primary Antibodies

    • 库存

      Available

    • 供应商

      Elucigen Biosciences

    • 宿主

      Rabbit

    • 应用范围

      ICC, WB

    • 浓度

      0.5 mg/mL

    • 靶点

      P23528

    • 抗体英文名

      Anti-Phospho-Cofilin (Ser3) Recombinant Rabbit Monoclonal Ab

    • 抗体名

      Anti-Phospho-Cofilin (Ser3) Recombinant Rabbit Monoclonal Ab

    • 规格

      25μg/100μg/500μg

    规格:25μg产品价格:¥860.0
    规格:100μg产品价格:询价
    规格:500μg产品价格:询价
    Cofilin is an actin-binding protein that promotes the severing and depolymerization of filamentous actin (F-actin), facilitating actin filament turnover essential for processes like cell motility, cytokinesis, and endocytosis. Phosphorylation at Ser3, primarily mediated by LIM kinases (LIMK) and testicular protein kinases (TESK), inhibits cofilin's ability to bind actin, thereby reducing its actin-severing activity and stabilizing actin filaments. This regulatory mechanism allows cells to modulate actin dynamics in response to various stimuli, impacting cellular processes such as migration, morphogenesis, and response to stress. Dysregulation of cofilin phosphorylation has been implicated in pathological conditions, including cancer metastasis and neurodegenerative diseases. Detection of Phospho-Cofilin (Ser3) levels is commonly employed to assess the activation state of cofilin and the dynamics of actin remodeling in cells.​

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    图标文献和实验
    该产品被引用文献
    Yang, N. et al. (1998) Nature 393, 809-12.
    相关实验
    • 【求助】抗体名称Ab-33是什么意思?

      : 这个抗体是非磷酸化的抗体non-phospho-antibody ,33 代表的是基因位点 感觉不应该说“33 代表的是基因位点”,准确的说是指:该抗体的免疫原是合成非磷酸化的β-Catenin的33位丝氨酸附近的多肽。 Anti β-Catenin (Ab-33) Immunogen:Synthesized non-phosphopeptide derived from human β-Catenin

    • Expression and Isolation of Recombinant Antibody Fragments in E. coli

      Central to the rapid growth in the study and application of recombinant antibodies in recent years is the ability to reliably and cost-effectively produce large quantities of functional protein. In contrast to glycosylated whole monoclonal

    • 如何做出一手漂亮的 WB 结果?

      到 PVDF 膜上,同时减少蛋白不必要降解,这对于最终获得清晰、可信结果也是需要考虑因素。抗体信息:1.ACC1, Recombinant Rabbit monoclonal IgG. HuaAn. HuaAn biotechnology , inc.2.ATGL, Mouse mAb IgG1, Cat#:RT1058. HuaAn biotechnology , inc.3.p-PERK(Thr981), Rabbit Polyclonal IgG primary antibodies, Cat

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    文献支持
    Anti-Phospho-Cofilin (Ser3) Recombinant Rabbit Monoclonal Ab
    ¥860