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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the N-terminal region of human RHOT1.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat (predicted)
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0638
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
Q8IXI2
- 抗体英文名:
Anti-RHOT1 / MIRO-1 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-RHOT1 / MIRO-1 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Mitochondrial Rho GTPase 1 (RHOT1), also known as MIRO1, is a mitochondrial outer membrane protein that regulates mitochondrial transport, calcium signaling, and quality control. It anchors mitochondria to motor proteins like kinesin and dynein via TRAK adaptors, facilitating their movement along microtubules . RHOT1 contains two GTPase domains and EF-hand motifs that bind calcium, enabling it to respond to intracellular calcium levels and halt mitochondrial movement when necessary . It also plays a role in mitophagy by interacting with PINK1 and Parkin to remove damaged mitochondria . Mutations in RHOT1 have been linked to Parkinson’s disease and cancer progression.
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文献和实验该产品被引用文献
Nguyen, TT., et al. (2014). Proc. Natl. Acad. Sci. USA. 111(35); E3631-E3640.
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Anti-RHOT1 / MIRO-1 Recombinant Rabbit Monoclonal Ab
¥860





