- ￥860
- Elucigen Biosciences
- ERB0445
- 2025年08月13日
- ICC, WB
- Rabbit
- Human, Mouse, Rat (predicted)
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide corresponding to the region surrounding phosphoserine 724 from the C-terminal, cytoplasmic domain of human IRE-1a.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat (predicted)
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
ERB0445
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
Elucigen Biosciences
- 宿主：
Rabbit
- 应用范围：
ICC, WB
- 浓度：
0.5 mg/mL
- 靶点：
O75460
- 抗体英文名：
Anti-Phospho-IRE-1α (Ser724) Recombinant Rabbit Monoclonal Ab
- 抗体名：
Anti-Phospho-IRE-1α (Ser724) Recombinant Rabbit Monoclonal Ab
- 规格：
25μg/100μg/500μg
| 规格： | 25μg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | 询价 |
| 规格： | 500μg | 产品价格： | 询价 |
Phospho-IRE1α (Ser724) refers to the phosphorylated form of IRE1α (Inositol-requiring enzyme 1α), a key protein involved in the unfolded protein response (UPR), a cellular stress response activated by the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Phosphorylation of IRE1α at Ser724 is a critical modification that regulates its activity in response to ER stress. When activated, IRE1α induces X-box binding protein 1 (XBP1) splicing, leading to the expression of genes involved in protein folding, quality control, and degradation. This process helps restore ER homeostasis. The phosphorylation of IRE1α at Ser724 is important for modulating its function and is a subject of research in contexts like neurodegenerative diseases, cancer, and metabolic disorders, where ER stress plays a significant role in pathogenesis.
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文献和实验该产品被引用文献
Alsamri, H. et al (2022) Front Oncol. 12:911615.
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Anti-Phospho-IRE-1α (Ser724) Recombinant Rabbit Monoclonal Ab
￥860
