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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the cytoplasmic domain of human FUNDC1.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Rat, Mouse (predicted)
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0424
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
Q8IVP5
- 抗体英文名:
Anti-FUNDC1 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-FUNDC1 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
FUN14 domain-containing protein 1 (FUNDC1) is a mitochondrial protein that plays a critical role in regulating mitophagy, the process by which damaged or dysfunctional mitochondria are selectively degraded to maintain cellular homeostasis. FUNDC1 is involved in the quality control of mitochondria and is essential for mitochondrial dynamics, including the regulation of mitochondrial fission and fusion. It functions as a receptor for mitophagy by interacting with various proteins that promote the removal of damaged mitochondria. Additionally, FUNDC1 is implicated in cellular responses to hypoxia and stress, and its dysregulation has been linked to several diseases, including neurodegenerative disorders and cardiovascular diseases.
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文献和实验该产品被引用文献
Chen, M. et al. (2016) Autophagy 12, 689-702.
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文献支持
Anti-FUNDC1 Recombinant Rabbit Monoclonal Ab
¥860




