- ￥2000 - 3200
- Solarbio|ElaBoX
- 31.2-2，000pg/mL
- 15pg/mL
- SEKRT-0213
- 北京
- 2025年08月13日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 检测范围：
31.2-2，000pg/mL
- 检测方法：
ELISA
- 应用：
ELISA
- 适应物种：
Rabbit
- 标记物：
ANP
- 样本：
血清/血浆/细胞培养上清
- 灵敏度：
15pg/mL
- 规格：
48T/96T
| 规格： | 48T | 产品价格： | ￥2000.0 |
|---|---|---|---|
| 规格： | 96T | 产品价格： | ￥3200.0 |
| 基本信息 | |
| 中文名称 | 兔心钠肽检测试剂盒 |
| 英文名称 | Rabbit ANP ELISA Kit |
| 别名 | ANF; ANP; ANPatriopeptin; ATFB6; atrial natriuretic factor; Atrial Natriuretic Peptide; Cardionatrin; CDD-ANF; natriuretic peptide A; natriuretic peptide precursor A; NPPA; PND; PNDcardionatrin; prepronatriodilatin |
| 储存条件 | 2-8℃，6 months |
| 检测目标 | ANP |
| 样品类型 | 血清/血浆/细胞培养上清 |
| 反应性 | Rabbit |
| 应用 | ELISA |
| 定量/定性 | 定量检测 |
| 检测范围 | 31.2-2，000pg/mL |
| 灵敏度 | 15pg/mL |
| 精密度 | 板内，板间变异系数均<10% |
| 回收率 | 80%-120% |
| 反应时间 | 3h30min |
| Swiss Prot | P07500 |
| Gene ID | 100009087 |
| 研究领域 | 信号传导;心血管 |
| 背景说明 | Atrial natriuretic peptide (ANP) is a powerful vasodilator, and a protein hormone secreted by heartmuscle cells. It is involved in the homeostatic control of body water, sodium, potassium and adiposetissue. It is released by atrial myocytes in response to high blood volume. ANP acts to reduce the water,sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP has exactlythe opposite function of the aldosterone secreted by the zona glomerulosa in regard to its effect on sodiumin the kidney that is, aldosterone stimulates sodium retention and ANP generates sodium loss.Incardiac myocytes, ANP is made as a precursor form, i.e. prepro-ANP, a polypeptide of 151 aminoacids. After the signal peptide is removed in the endoplasmic reticulum, the 126-amino-acid pro-ANPis stored in the intracellular granules. When the cells are stimulated, pro-ANP is released and converted tothe 28-amino-acid C-terminal mature ANP on the cell surface by the cardiac transmembrane serineprotease corin.ANP interacts with three receptors including guanylyl cyclase-A (NPR1), guanylylcyclase-B (NPR2), natriuretic peptide clearance receptor (NPR3). The binding of ANP to its receptorcauses the conversion of GTP to cGMP and raises intracellular cGMP. Receptor-agonist binding causes areduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure.Lipolysis is increased and renal sodium reabsorption is decreased. The overall effect of ANP on the bodyis to counter increases in blood pressure and volume caused by the renin-angiotensin system. ANP andrelated peptides are used as biomarkers for cardiovascular diseases such as stroke, coronary arterydisease, myocardial infarction and heart failure. |
| 单位 | 盒 |
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