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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期:
1 year
- 英文名:
Recombinant Mouse TFPI Protein, C-Fc
- 库存:
999
- 供应商:
abinScience
- 规格:
100ug

| Product name | Recombinant Mouse TFPI Protein, C-Fc |
|---|---|
| Catalog No. | MY403021 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >95% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | O54819 |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Alternative Names | Tissue factor pathway inhibitor, TFPI, Extrinsic pathway inhibitor, EPI, Lipoprotein-associated coagulation inhibitor, LACI, Tfpi |
| Species | Mus musculus (Mouse) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
Product categories and application fields.
Main products...
Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• TFPI-dependent activities of protein S., PMID:22425215
• TFPI blockade: removing coagulation's brakes., PMID:31778542
• Anti-tissue factor pathway inhibitor (TFPI) therapy: a novel approach to the treatment of haemophilia., PMID:30302740
• Regulation of TFPI function by protein S., PMID:19630792
• Longitudinal observations of TFPI levels in paediatric Haemophilia A patients., PMID:37335569
• Tissue factor/TFPI and blood cells., PMID:22197177
• Hemostatic properties of a TFPI antibody., PMID:22405586
• Concizumab: a novel anti-TFPI therapeutic for hemophilia., PMID:33570646
• Tissue factor pathway inhibitor (TFPI)--an update., PMID:8979119
个富含碱性氨基酸的C端序列共同构成TFPI分子。 TFPI二级结构 TFPI的抗凝活性主要与K1和K2结构域有关。K2能够直接与FXa结合并抑制其活性.形成FXa/TFPI复合物;K1则是FXa/TFPI复合物中TFPI分子与FVIIa/TF结合并抑制其活性的结构基础;K3和C末端除了与TFPI的抗凝活性有一定关系之外,还能与肝素、低密度脂蛋白、LRP和CDl4等分子结合,主要与TFPI在肝脏的代谢有关,并且赋予其抗炎的生物学活性。 此外,TFPI在第117、167
depends on product and its function. N-terminal sequencing revealed that the purified rBoNTC(Hc )-N is missing the first eight amino acids of the N-terminus of the protein, whereas the purified rBoNTC(Hc )-C protein is intact. After a mouse bioassay test
总蛋白(包括质膜和细胞器膜蛋白),但费时费力。目前,有一种最新型有效的膜蛋白提取工具,并具有高纯度、高特异性、高载量温和提取的优点。是基于1980年科学家在牛眼视网膜中发现的一种命名为Rho1D4的氨基酸序列以及其对应的抗体来作为亲和标签纯化膜蛋白取得了非常好的效果,将Rho1D4抗体链接在琼脂糖或磁珠上,用于亲和层析带有Rho1D4标签的膜蛋白,能近乎完美的解决这些研究难题。1) 什么是Rho1D4?Rho1D4是指在牛眼视网膜细胞内的牛视紫红质C端的最后九位氨基酸。Rho1D4得名于与该序列
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