- ￥1868
- abinScience
- France
- HA630012
- 2026年03月03日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期：
1 year
- 英文名：
Recombinant Human NAA10 Protein, N-His
- 库存：
999
- 供应商：
abinScience
- 规格：
100ug
| Product name | Recombinant Human NAA10 Protein, N-His |
|---|---|
| Catalog No. | HA630012 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | P41227 |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Alternative Names | N-alpha-acetyltransferase 10; 2.3.1.255; N-terminal acetyltransferase complex ARD1 subunit homolog A; hARD1; NatA catalytic subunit Naa10; NAA10; ARD1; ARD1A; TE2 |
| Species | Homo sapiens (Human) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
Product categories and application fields.
Main products...
Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• Expanding the phenotypic spectrum of NAA10-related neurodevelopmental syndrome and NAA15-related neurodevelopmental syndrome., PMID:37130971
• NAA10 as a New Prognostic Marker for Cancer Progression., PMID:33126484
• ARD1/NAA10 acetylation in prostate cancer., PMID:30054487
• LncRNA RGMB-AS1 inhibits HMOX1 ubiquitination and NAA10 activation to induce ferroptosis in non-small cell lung cancer., PMID:38574881
• NAA10 (N-Alpha-Acetyltransferase 10): A Multifunctional Regulator in Development, Disease, and Cancer., PMID:40558489
• ARD1/NAA10 in hepatocellular carcinoma: pathways and clinical implications., PMID:30054466
• N-α-acetyltransferase 10 (NAA10) in development: the role of NAA10., PMID:30054454
• NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas., PMID:37253389
• Versatility of ARD1/NAA10-mediated protein lysine acetylation., PMID:30054464
干货 | CUT and Tag 核心酶 Hyperactive PA/PG-Tn5 Transposase 大解密
CUT&Tag（Cleavage Under Targets and Tagmentation）是蛋白-DNA 互作的一大革新技术，它不需要使用甲醛交联以及免疫共沉淀，而是通过针对靶蛋白（如转录因子、染色质重塑蛋白）的抗体和 Protein A/G 的介导，使得与 Protein A/G 融合的 Tn5 酶(Tagmentase)在切割 DNA 片段的同时在序列两端加上测序接头，经 PCR 扩增后即可形成用于高通量测序的文库（见图 1 ）。CUT &Tag 技术具有细胞投入量低、信噪
的分离速度，但是附加PA10时分离速度有明显加快，KD値也会增大。 亲和标记法的确立使用单克隆抗体和肽标记的亲和标签系统有很多要求，具体来说要求如下：1）高特异性，能从众多杂质中得到目的蛋白；2）高亲和性，结合了的标记蛋白不会马上分离；3）能够在洗脱时保持蛋白活性；4）为了降低成本，色谱柱希望能多次循环再生使用。等等，能满足以上条件，就是一个好的亲和标签系统。首先，作为NZ-1的抗原使用的14个氨基酸残基的肽需要决定最短长度，长度越短使用越方便，对附加tag的蛋白的影响也越小。从加藤等人以前使用
High Throughput Production of Recombinant Human Proteins for Crystallography
This chapter presents in detail the process used in high throughput bacterial production of recombinant human proteins for crystal structure determination. The core principles are: (1 ) Generating at least 10 truncated constructs
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