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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 保质期:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 英文名:
Histone H1-derived Peptide, phosphorylated
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
10mg/5mg/1mg
| 规格: | 10mg | 产品价格: | ¥6230.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥4450.0 |
| 规格: | 1mg | 产品价格: | ¥1780.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.53917-42-3 |
| 单字母序列 | RPVKVYPNGAEDESAEAFPLEF |
| 三字母序列 | Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe |
| 别名 | Adrenocorticotropic Hormone (18-19), human |
| 分子式 | C112H165N27O36 |
| 分子量 | 2465.7 |
| 纯度 | ≥98% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 溶解性 | H2O:100 mg/mL; *超声助溶; |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 促肾上腺皮质激素(ACTH) |
| 规格 | Adrenocorticotropic Hormone (ACTH) (18-39), human 是一种似皮质促素中叶肽,产生于垂体中叶的促黑素细胞。Adrenocorticotropic Hormone (ACTH) (18-39), human is a corticotropinlike intermediate lobe peptide, which is produced in the melanotrophs of the intermediate lobe of the pituitary. |
| In Vitro | The ACTH family of polypeptides consists of ACTH(1-39) (adrenocorticotropin), ACTH (1-13)amide (α-melanotropin;α-MSH); and ACTH (18-39) (corticotropinlike intermediate lobe peptide, CLIP). These polypeptides are derived from a common precursor, proopiomelanocortin. In corticotropic cells of the pars distalis, proopiomelanocortin (POMC) undergoes a series of proteolytic cleavage reactions to yield ACTH (1-39) as a major end product. However, in the melanotropic cells of the pars intermedia, an additional set of proteolytic reactions results in the conversion of ACTH (1-39) to ACTH (1-13) amide and ACTH (18-39). In several species of vertebrates, ACTH (1-13) amide undergoes end product modification to yield mono- and diacetylated forms ofα-MSH as major end products in the pars intermedia. |
| 单位 | 瓶 |
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文献和实验Peptide Pull-Down (PPD) Assay for Identification and Characterization of Histone PTM Effectors
PTMs and their effectors play in biological processes. An important component of this understanding will come through identification of histone PTM binding proteins. To this end, the peptide pull-down (PPD) assay provides a simple and effective tool
activity measurements. Here we provide protocols for precipitation of fluorescent fusion proteins from crude cell extracts to identify and map protein–protein interactions as well as specific histone tail peptide binding in an easy and reliable manner.
的研究已经成为蛋白质科学的热点之一。 磷酸化多肽(主要指肽链中的酪氨酸、丝氨酸和苏氨酸残基的侧链羟基被磷酸化生成酸式磷酸酯的修饰多肽)是研究蛋白质磷酸化过程的必不可少的工具,它可作为磷酸酶模型底物,或作为可产生抗磷酸化蛋白抗体的抗原,也可以在确定磷酸化蛋白的物理参数时作为参考化合物等[3]。因此磷酸化多肽的合成在过去的几年中吸引了相当大的兴趣,目前已确定了较为成熟的合成路线,使磷酸化多肽的合成趋于常规。目前磷酸化多肽的合成主要有两个策略:后磷酸化法(Global
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