- ￥4980 - 32380
- Sino Biological
- 北京
- 10707-H02H-UE
- 2026年06月26日
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- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Human EPOR / Erythropoietin Receptor Protein (Fc Tag), Endotoxin-Free
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
100 µg/1 mg
| 规格： | 100 µg | 产品价格： | ￥4980.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥32380.0 |
蛋白名称：重组人EPOR / Erythropoietin Receptor蛋白(Fc标签)
蛋白构建：A DNA sequence encoding the extracellular domain (Ala25-Pro250) of human erythropoietin receptor (NP_000112.1) precursor was expressed with the C-terminal fused Fc region of human IgG1.
表达宿主：HEK293 Cells
蛋白纯度：≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-MALS(Routinely tested).
蛋白活性：1.Immobilized Recombinant Human EPOR / Erythropoietin Receptor Protein (Fc Tag)(Cat: 10707-H02H-UE) at 2 μg/mL (100 μL/well) can bind Recombinant Cynomolgus Erythropoietin / EPO Protein (His Tag) (Cat: 90133-C08H), the EC50 is 3.0 ng/mL (Routinely tested). 2.Measured by its ability to inhibit Epodependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is 2.6ng/ml in the presence of 0.1 U/mL Recombinant Human EPO.(Routinely tested).
蛋白内毒素：< 0.5 EU per mg protein.
预测N端：Ala 25
蛋白分子量：The recombinant human EPOR/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. The reduced monomer consists of 460 amino acids and has a predicted molecular mass of 51.97 kDa. As the result of glycosylation, the band migrates approximately 50-60 in the SDS-PAGE under reducing conditions. The molecular weight of this protein is around 110.3 kDa verified by SEC-MALS(Routinely tested).
蛋白NP号：NP_000112.1
蛋白氨基酸序列：Ala25-Pro250
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文献和实验请教一个弱智的问题, 帮忙把genebank上查的report逐个解释一下, 不要遗漏信息!
LOCUS NM_017002 1524 bp mRNA linear ROD 28-OCT-2004 DEFINITION Rattus norvegicus erythropoietin receptor (Epor), mRNA. ACCESSION NM_017002 VERSION NM_017002.1 GI:8393318 KEYWORDS . SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus
白细胞介素-2（interleukin rhlL-2，IL-2）主要由活化的T淋巴细胞分泌的一种糖蛋白，是调节机体免疫功能最主要的淋巴因子之一。天然IL-2含有糖基，基因重组IL-2不含糖基，由133个氨基酸组成，相对分子质量为15KD。IL-2在机体应答，免疫调节和抗肿瘤免疫中具有十分重要的作用。临床用于多种恶性实体肿瘤。重组人IL-2是一种重组人白细胞介素-2的生物制品，一般制备成粉针剂应用，其规格以活性单位而不是以重量单位标示。本研究拟通过双抗体放射免疫分析法又称为免疫沉淀法测定注射
Epo and Non-hematopoietic Cells: What Do We Know
with targeted deletion of Epo or the Epo receptor (EpoR) show impaired erythropoiesis, lack mature erythrocytes, and die in utero around embryonic day 13.5 (Wu et al. Cell 83:59–67, 1995; Lin et al. Genes Dev. 10:154–164, 1996
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