- ￥1092 - 21120
- Solarbio
- P01249
- 北京
- 2025年07月25日
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- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥3276.0 |
| 规格： | 10ug | 产品价格： | ￥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | UPP1 Protein;Uridine Phosphorylase 1;UPP1 |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM Tris, 200mM NaCl, 1mM DTT, pH 8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase.UPP1 catalyses the reversible phosphorolysis of uridine to uracil.The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues.The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers，such as oral squamous cell carcinoma.UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios.UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验万蕊雪/施一公等再发Science开辟新「地图」，这几个领域将直接受益
论文 Structure of the activated human minor spliceosome，利用单颗粒冷冻电镜技术重构出了世界上首个次要剪接体的冷冻电镜结构，整体分辨率高达 2.9 埃，并搭建了第一个次要剪接体的原子模型，其中包含了 4 条 RNA 和 45 个蛋白。[8] 图片来源：Science这项研究首次从原子分辨率展示了人源次要剪接体的组成和它与相应内含子的识别机制。更重要的是，它针对的是活化的人源次要剪接体，对于催化中心及活性位点进行了分析，对于药物靶点设计应用具有不可估量的作用。另外课题
Microarray Approaches for Analysis of Cell Cycle Regulatory Genes
genes is also known to play an important role in disease states such as genomic instability and cancer. For instance, p53, a cell cycle regulatory transcription factor, is also one of the most commonly mutated tumor-suppressor genes in human cancer
(9): 1245–53. doi:10.1101/gr.6406307. PMID 17690206. ^ Bertone P, Stolc V, Royce TE, Rozowsky JS, Urban AE, Zhu X, Rinn JL, Tongprasit W, Samanta M, Weissman S, Gerstein M, Snyder M (December 2004). "Global identification of human transcribed sequences
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