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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥3276.0 |
| 规格: | 10ug | 产品价格: | ¥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Calnexin;IP90;Major Histocompatibility Complex Class I Antigen-Binding Protein p88;p90;CANX |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, 10% Glycerol, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family.It consists of a large N-terminal calcium-binding lumenal domain,a single transmembrane helix and a short (90 residues),acidic cytoplasmic tail.The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum.Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum.Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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