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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥3276.0 |
| 规格: | 10ug | 产品价格: | ¥1092.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting; |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family.STING is 379 amino acids (aa) in length.It contains an N-terminal cytoplasmic region (aa 1-20),four transmembrane segments (aa 21-173),and a C-terminal cytoplasmic domain (aa 174-379).It ubiquitously expressed in skin endothelial cells,alveolar type 2 pneumocytes,bronchial epithelium and alveolar macrophagesand.Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I,MAVS and SSR2,RNF5 and TRIM56 along with TBK1.This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验motifs located prevalently in the 3′ untranslated regions of target messenger RNAs (mRNA). Interferon-alpha-2a (IFNα) induces a large set of protein coding genes mediating antiproliferative and antiviral responses. Here we use a global microarray-based
Microarray Approaches for Analysis of Cell Cycle Regulatory Genes
genes is also known to play an important role in disease states such as genomic instability and cancer. For instance, p53, a cell cycle regulatory transcription factor, is also one of the most commonly mutated tumor-suppressor genes in human cancer
Method for Single-Cell Electroporation
electrodes approx 1 x 2 mm soldered to electric leads (for wiring to stimulator and capacitor) and mounted on a rod for use with a micromanipulator. Micromanipulators: Two coarse X, Y, Z manipulators. One to hold the pressure injection
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