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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥14400.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥10080.0 |
| 规格: | 50ug | 产品价格: | ¥1560.0 |
| 规格: | 10ug | 产品价格: | ¥780.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Parathyroid hormone;PTH;Parathormone;Parathyrin;PTH |
| 中文名称 | Recombinant Human Parathyroid Hormone/PTH |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis.Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid.This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney.Another hormone,parathyroid hormone-related protein,binds to the same receptor as parathyroid hormone and has major effects on development.Like most other protein hormones,parathyroid hormone is synthesized as a preprohormone.After intracellular processing,the mature hormone is packaged with in the Golgi into secretory vesicles,the secreted into blood by exocytosis.In renal epithelium,PTH promotes conversion of Vitamin D to its active form,lowers Ca++ excretion and increases phosphate excretion.PTH also increases hematopoietic stem cell proliferation and mobilization and induces arterial vasodilation by regulating Ca++ influx in PTH1R-expressing arterial smooth muscle. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验北京时间 2022 年 2 月 9 日,中国科学院深圳先进技术研究院脑认知与脑疾病研究所、深港脑科学创新研究院杨帆课题组在 Nature Communications 上发表题为 An optogenetic approach for regulating human parathyroid hormone secretion 的最新研究成果。 研究团队历时 5 年,创新性地将光遗传技术运用于甲状旁腺素(Parathyroid Hormone, PTH)的分泌调控,通过精准节律性调节
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