P01126 Recombinant Mouse Inter
leukin-1 receptor type 1/IL-1R-1/IL-1RT1/IL-1 RI/CD121a 细胞因子/蛋白- ￥988 - 21120
- Solarbio
- P01126
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Interleukin-1 receptor type 1;IL-1R-1;IL-1RT1;IL-1 RI;CD121a |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse Interleukin 1 receptor，type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a)，is an interleukin receptor.IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family.This protein is a receptor for interleukin 1 alpha (IL1A)，interleukin 1 beta (IL1B)，and interleukin 1 receptor antagonist (IL1RA).It is an important mediator involved in many cytokine induced immune and inflammatory responses.An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1α or IL1βbut not IL1ra，was identified.This Type I receptor complex appears to mediate all the known IL1 biological responses.The receptor Type II has a short cytoplasmic domain and does not transduce IL1 signals.In addition to the membranebound form of IL1 RII，a naturallyoccurring soluble form of IL1 RII has been described.It has been suggested that the Type II receptor，either as the membranebound or as the soluble form，serves as a decoy for IL1 and inhibits IL1 action by blocking the binding of IL1 to the signaling Type I receptor complex. |
| 来源 | Human Cells |
| 溶剂 | Dissolve the lyophilized protein in distilled water. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验randomly paired light (L) and heavy (H) chain coding regions under transcriptional control of P lac . The H chain coding region is fused in-frame with the phage gene, Δ gIII , coding for a truncated version of the phage surface protein pIII (ΔpIII
Genetic and Pharmacologic Models for Type 1 Diabetes
. , Burton, A.R. , Vincent, E. , Arnold, P.Y. , Santamaria, P. , and Vignali, D.A. 2009. T cell islet accumulation in type 1 diabetes is a tightly regulated, cell‐autonomous event. Immunity 31: 643‐ 653.
Overview of Receptor Allosterism
: Taking advantage of permissive receptor pharmacology. Trends. Pharmacol. Sci. 28:382‐389. Lefkowitz, R.J., Cotecchia, S., Samama, P., and Costa, T. 1993. Constitutive activity
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