- ￥988 - 21120
- Solarbio
- P01071
- 北京
- 2025年07月25日
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￥676
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Interleukin-23 receptor;IL23R;IL-23 receptor;IL-23R |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23.IL23 receptor complex is comprised of two subunits，the IL12Rβ1 subunit，which is shared with several cytokines，and a subunit that is unique to IL-23.IL23，after binding to IL23R，activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes.IL23R is expressed on T cells，NK cells，dendritic cells，and macrophages.In fact，polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis，multiple sclerosis，Graves's ophtalmopathy and inflammatory bowel diseases.The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【进展|热点】Immunity:IL-17A和IL-17F的表达调控机制不同
22、IL-21以及Th17特异性的转录因子ROR-γt以及ROR-α，但是合成IL-17A的能力受损。通过观察Itk缺失的细胞对TGF-β和IL-6的反应性后，作者发现其IL-17A合成受损与细胞因子信号通路关系不大。令人感到意外的是，作者发现：采用钙通道激活剂能修复Itk缺失的细胞IL-17A合成的缺陷，而采用钙通道激活剂FK506则能使野生型Th17细胞合成IL-17A的能力受损，表现出和Itk缺失的细胞相似的表型。联系到，Itk是TCR的重要信号分子，其下游存在钙离子依赖性信号转导途径
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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