P01057 Recombinant Mouse Trigg
ering Receptor Expressed on Myeloid Cells 2b/TREM-2b 细胞因子/蛋白- ￥988 - 21120
- Solarbio
- P01057
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Triggering Receptor Expressed on Myeloid Cells 2b;Triggering receptor expressed on myeloid cells 2;TREM-2;Triggering receptor expressed on monocytes 2;Trem2;Trem2a;Trem2b;Trem2c;TREM-2b |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages，osteoclasts，microglia and dendritic cells.TREM-2 is one member of the TREM family，inhibiting the releasing of inflammatory mediators，so it is an important in vivo anti-inflammatory receptor.TREM-2 consists of an 18 aa signal sequence，a 153 aa extracellular domain (ECD) with one V-type Ig-like domain，a 21 aa transmembrane (TM) domain，and a 35 aa cytoplasmic tail.A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161.TREM-2 transduces intracellular signals through the adaptor DAP12.After binding of TREM-2 with ligand，the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions，which then activate the myeloid cells and participate T cell responses. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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