产品封面图

P01044 Recombinant Mouse Chord

in-like protein 2/CHL2/CHRDL2 细胞因子/蛋白
收藏
  • ¥988 - 21120
  • Solarbio已认证
  • P01044
  • 北京
  • 2025年07月25日
    avatar
    品牌商
    14钻石会员
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名Chordin-like protein 2;BNF-1;CHRDL2;chordin-like 2;chordin-like protein 2
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Mouse Chordin-Like 2,also known as CHL2,is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis.The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25 aa signal peptide.The mature chain of CHL2 protein contains two potential N-linked glycosylation sites,one putative NLS and three 63 aa cysteine-rich von Willebrand type C repeats (CRs).CHL2 gene is weakly expressed in the liver and kidney,partly expressed in the connective tissues of reproductive organs such as ligaments of the ovary and oviduct in females,and of testis,epididymis and certain male accessory sex glands in males.Recombinant mCHL2 protein interacted directly with five BMPs and one GDF thereby inhibiting,in vitro,several BMP/GDF-dependent processes including,osteogenic differentiation of C2C12 mesenchymal progenitor cells by several BMPs,ATDC5 embryonal carcinoma cells by GDF5 and BMP4-dependent lymphohematopoietic (CD34+CD31hi and CD34+CD31lo) progenitor cell development from ES cells.CHL2 may inhibits BMPs activity by blocking their interaction with their receptors,and has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells,by preventing or reducing the rate of matrix accumulation.Also,it may play a role during myoblast and osteoblast differentiation,and maturation.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥760
    上海羽哚生物科技有限公司
    2025年07月13日询价
    ¥4854
    上海嵘崴达实业有限公司
    2025年11月24日询价
    ¥832
    北京索莱宝科技有限公司
    2025年07月25日询价
    询价
    MedChemExpress LLC
    2025年07月14日询价
    ¥640
    苏州近岸蛋白质科技股份有限公司
    2025年11月02日询价
    P01044 Recombinant Mouse Chordin-like protein 2/CHL2/CHRDL2 细胞因子/蛋白
    ¥988 - 21120