- ￥988 - 21120
- Solarbio
- P01029
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Cytoplasmic antiproteinase 3;Peptidase inhibitor 9;CAP3;PI-9;Serpin B9 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Serpin B9，also known as Cytoplasmic antiproteinase 3(CAP-3)，is a cytoplasm protein which belongs to the large superfamily of serine proteinase inhibitors (serpins)，which bind to and inactivate serine proteinases.Serpin B9 is an inhibitor of the granzyme B/perforin lytic pathway.It is expressed in normal mammary epithelial cells but not in most mammary carcinoma cell lines.These interactions are involved in many cellular processes，including coagulation，fibrinolysis，complement fixation，matrix remodeling，and apoptosis.Serpin-B9 expression in immune-privileged cells，APCs，and CTLs protects these cells against the actions of granzyme B，and when expressed in tumor cells or virally infected hepatocytes，confers resistance to killing by CTL and NK cells.Expression of increasing levels of Serpin-B9 in target cells may progressively inhibit immune surveillance by blocking NK and CTL-induced cytotoxicity through the perforin / granzyme pathway and then through the Fas / FasL pathway. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P01029 Recombinant Human Serpin B9 细胞因子/蛋白
￥988 - 21120
