- ￥936 - 21120
- Solarbio
- P00885
- 北京
- 2025年07月25日
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￥585
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Thrombospondin-1;THBS1;TSP;TSP1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥85% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer.TSP-1 regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM).TSP-1 contains an N-terminal Laminin G-like globular domain，an extended central region with one vWFC domain，3 TSP type 1domains，2 EGF-like domains，and 8 TSP type3 domains，and a globular TSP C-terminal domain.Distinct regions of TSP-1 have been associated with binding to particular ECM or cellular molecules.TSP-1 counteracts the angiogenic，hypotensive，and antithrombotic effects of nitric oxide (NO).It binds and neutralizes VEGF，blocks VEGF R2 signaling on vascular endothelial cells(EC)，and destabilizes adhesive contacts between EC.TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP). |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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