P00850 Recombinant Human Delta-like 1/DLL1 细胞因子/蛋白

P00850 Recombinant Human Delta

-like 1/DLL1 细胞因子/蛋白
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  • ¥936 - 21120
  • Solarbio已认证
  • P00850
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥936.0
    基本信息
    基因名
    别名Delta-like protein 1;Drosophila Delta homolog 1;Delta1;H-Delta-1;DLL1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM Hepes, 150mM NaCl, 1mM EDTA, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Delta-like protein 1 (DLL1) is a type I transmembrane protein that belongs to the Delta/Serrate/Lag2 (DSL) family of Notch ligands.Mature human DLL1 consists of a 528 amino acid (aa) extracellular domain (ECD) with one DSL domain and eight EGF-like repeats,a 23 aa transmembrane segment,and a 155 aa cytoplasmic domain.Within the ECD,human DLL1 shares 91% aa sequence identity with mouse and rat DLL1.The residual membranebound portion of DLL1 can be cleave by presenilin-dependent γ-secretase,enabling the cytoplasmic domain to migrate to the nucleus.DLL1 localizes to adherens junctions on neuronal processes through its association with the scaffolding protein MAGI1.DLL1 is widely expressed,and it plays an important role in embryonic somite formation,cochlear hair cell differentiation,plus B and T lymphocyte differentiation.The upregulation of DLL1 in arterial endothelial cells following injury or angiogenic stimulation is central to postnatal arteriogenesis.DLL1 is also overexpressed in cervical carcinoma and glioma and contributes to tumor progression.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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