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P00805 Recombinant Human CD300

b/CD300LB/LMIR5 细胞因子/蛋白
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  • ¥897 - 18600
  • Solarbio已认证
  • P00805
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥18600.0
    规格:500ug产品价格:¥12420.0
    规格:50ug产品价格:¥2704.0
    规格:10ug产品价格:¥897.0
    基本信息
    基因名
    别名CD300b;CLM-7;CLM-7;CMRF35-A2;IREM-3;IREM3;TREM-5;TREM5;CD300LB
    中文名称Recombinant Human CD300b/CD300LB/LMIR5
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明CD300LB,also known as CD300b,LMIR5,CLM-7,and IREM-3,is a glycoprotein member of the immunoglobulin superfamily.LMIR5 is expressed on the surface of myeloid lineage cells.It forms noncovalent cis-homodimers and cis-heterodimers with other CD300 family proteins,and the composition of these dimers affects the cellular response.Antibody cross-linking of LMIR5 induces mast cell granule release and cytokine production as well as its tyrosine phosphorylation of LMIR5 (in human).LMIR5 interacts with TIM1 and TIM4 which regulate T cell activation and are themselves binding partners.TIM1 interactions with LMIR5 mediate mast cell activation and the accumulation of neutrophils at sites of TIM1 up-regulation on damaged renal tubule epithelial cells.Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP,and also independently by recruitment of GRB2.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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