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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥12000.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥8640.0 |
| 规格: | 50ug | 产品价格: | ¥2340.0 |
| 规格: | 10ug | 产品价格: | ¥780.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | COLEC7;Collectin 7;Lung surfactant protein D;PSPD;pulmonary surfactant-associated protein D;SFTPD;SPD;SP-D;SP-Dpulmonary surfactant apoprotein;surfactant protein D;surfactant,pulmonary-associated protein D; |
| 中文名称 | Recombinant Mouse Pulmonary Surfactant-associated Protein D/SP-D |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 7.4 . |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Pulmonary surfactant-associated protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators.Mouse SP-D cDNA encodes a 19 aa signal sequence and a 355 aa mature region with a 25 aa N-terminal linking-region,a 177 aa hydroxyproline and hydroxylysine collagen-like domain,a 46 aa coiled-coil segment,and a 106 aa,C-terminal collectin-like C-type lectin domain.SP-D is found in serum,plasma,broncho-alveolar lavage (BAL) fluid,and amniotic fluid.It also binds SIRP alpha and the calreticulin/CD91 complex on macrophages.SP-D contributes to the lung's defense against inhaled microorganisms,organic antigens and toxins.It Interacts with compounds such as bacterial lipopolysaccharides,oligosaccharides and fatty acids and modulates leukocyte action in immune response.It may participate in the extracellular reorganization or turnover of pulmonary surfactant.It binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.HPLC:------The purity of Human SIRPA-Fc(Cat#CP68)is greater than 95% as determined by SEC-HPLC. |
| 单位 | 支 |
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文献和实验Purification of Surfactant Protein D (SP-D) from Pooled Amniotic Fluid and Bronchoalveolar Lavage
Surfactant protein SP-D is a multimeric collagenous lectin, called collectin . SP-D is a multifunctional, pattern recognition innate immune molecule, which binds in a calcium dependent manner to an array of carbohydrates and lipids
Purification of Native Surfactant Protein SP-A from Pooled Amniotic Fluid and Bronchoalveolar Lavage
Surfactant protein SP-A is a hydrophilic glycoprotein, similar to SP-D, which plays an important role in pulmonary surfactant homeostasis and innate immunity. SP-A is actively expressed in the alveolar type II cells and Clara cells
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
, A., Sopko, R., McCartney, R.R., Schmidt, M.C., Rachidi, N., Lee, S.J., Mah, A.S., Meng, L., Stark, M.J., Stern, D.F., De Virgilio, C., Tyers, M., Andrews, B., Gerstein, M., Schweitzer, B., Predki, P.F., and Snyder, M. 2005. Global analysis of protein
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