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- 文献和实验
- 技术资料
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 英文名：
CD24
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ¥780.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥2340.00 |
| 规格： | 500ug | 产品价格： | ¥8640.00 |
| 规格： | 1mg | 产品价格： | ¥12000.00 |
| 基因名 | CD24 |
| 别名 | Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A |
| 蛋白号 | P25063 |
| 种属 | Human |
| 宿主 | HEK293 |
| 产品描述 | Recombinant Human Signal Transducer CD24 is produced by our Mammalian expression system and the target gene encoding Ser27-Gly59(Ser44Thr) is expressed with a human IgG1 Fc tag at the C-terminus. |
| 区间范围 | Ser27-Gly59(Ser44Thr) |
| 标签信息 | C-Fc |
| 预测分子量 | 40-55 kDa |
| 表观分子量 | 40-55 KDa, reducing conditions |
| 纯度 | ≥95% by SDS‐PAGE. |
| 内毒素 | <1EU/ug as determined by LAL test. |
| 溶剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Signal Transducer CD24 is a heavily and variably glycosylated GPI-linked sialoprotein. Human CD24 is expressed on B lineage cells and granulocytes, on epithelial, neuronal, and muscle cells, and on a range of tumor cells. CD24 expression is regulated during lineage development and with the activation of various cell types. Antibody crosslinking of CD24 enhances the induction of apoptosis in B and T lymphocytes which contributes to negative selection and the induction of immune tolerance. CD24 on antigen presenting cells cooperates with B7 molecules in the costimulation of T cells. CD24 associates in cis with Siglec10 and with the danger-associated molecules HMGB1, HSP70, or HSP90 which are released from necrotic or damaged cells. Formation of these ternary complexes fills a protective role: the resulting Siglec10 signaling inhibits inflammatory responses that are otherwise induced by extracellular DAMPs. |
| 细胞活性 | No activity experimental data, to be verified. |
| ELISA活性 | Immobilized Anti-Human CD24 mAb at 2μg/ml (100μl/wel) can bind Human CD24 -Fc**: Biotinylated by NHS-biotin prior to testing The ED50 of Human CD24 -Fc* is 26.45 ng/ml. |
| SPR/BLI活性 | No activity experimental data, to be verified. |
| 研究领域 | 生物制药相关研究 |
| 英文名称 | CD24 |
| 中文名称 | CD24蛋白 |
| 单位 | 支 |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
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文献和实验Quantification of Human IgG and Related Fc Fusion Proteins by a Human IgG/Fc Capture ELISA
of recombinant human IgGs after production and purification for further assays. Here, we describe a human IgG/Fc capture enzyme linked immunosorbent assay (ELISA) which is simple, robust, inexpensive and specific for all types of human IgGs and related Fc fusion
CD24 分子 CD24 常用单克隆抗体或代号： BA- 1,ALB9 主要表达细胞： B,G [B] 分子质量(kDa)和结构： gp35- 45(GPI连接) 功 能： B细胞增殖和分化,结合CD62P,共刺激分子 CD24 Promotes antigen dependent proliferation of B cells; prevents differentiation
In this chapter we describe efficient procedures for the construction, expression and screening of comprehensive libraries of human Fab antibody fragments displayed on the surface of filamentous phage. Phagemid vectors are used for placing
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