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P00678 Recombinant Mouse Prola

ctin Receptor/PRLR 细胞因子/蛋白
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  • ¥780 - 17280
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  • P00678
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥17280.0
    规格:500ug产品价格:¥12096.0
    规格:50ug产品价格:¥1872.0
    规格:10ug产品价格:¥780.0
    基本信息
    基因名
    别名Prolactin receptor;PRL-R;Prlr;Prolactin R;PRLR
    中文名称Recombinant Mouse Prolactin Receptor/PRLR
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues.PRLRs are expressed in normal and neoplastic human breast tissue,and in most breast cancer cells.PRLR contains an extracellular region that binds prolactin,a transmembrane region,and a cytoplasmatic region required for the activation of the Jak2–Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes.PRLRs have also been observed in ovarian follicular cells of mice,pigs,sheep,deer,and humans,as well as in luteal tissue in cow and horse ovaries.Furthermore,PRLR knockout mice exhibit failure of embryonic implantation,reduced number of mature oocytes,and low fertilization rates.Knockout females also display a reduced number of primary follicles.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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