- ￥520 - 21120
- Solarbio
- P00508
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥21120.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥14784.0 |
| 规格： | 50ug | 产品价格： | ￥1560.0 |
| 规格： | 10ug | 产品价格： | ￥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Vascular Cell Adhesion Protein 1;V-CAM 1;VCAM-1;INCAM-100;CD106;VCAM1;L1CAM |
| 中文名称 | Recombinant Human CD106/VCAM-1/L1CAM |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM CaCl2, 2mM MgCl2, 5% Threhalose, pH 7.2. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | VCAM-1 is a single-pass type I membrane protein，contains 7 Ig-like C2-type domains.It is an endothelial ligand for very late antigen-4 (VLA-4) and α4-7 integrin expressed on leukocytes，and thus mediates leukocyte-endothelial cell adhesion and signal transduction.VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease，atherosclerosis，allograft rejection，infection，and asthmatic responses.During these responses，VCAM-1 forms a scaffold for leukocyte migration.VCAM-1 also activates signals within endothelial cells resulting in the opening of an endothelial cell gate through which leukocytes migrate.VCAM-1 has been identified as a potential anti-inflammatory therapeutic target，the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis.In addition，VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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