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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥10080.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥6912.0 |
| 规格: | 50ug | 产品价格: | ¥1560.0 |
| 规格: | 10ug | 产品价格: | ¥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | SDC4;Syndecan-4;SYND4;Ryudocan core protein |
| 中文名称 | Recombinant Mouse SDC4/Syndecan-4/SYND4/Ryudocan core protein |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥90% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Mouse SDC4 is a ubiquitous transmembrane proteoglycan which belongs to the syndecan proteoglycan family.SDC4 is a cell surface proteoglycan that bears heparan sulfate.The four vertebrate syndecans,Syndecan-1 through -4,have similar short cytoplasmic domains and extracellular portions that diverge,except for HS attachment sites.Structurally diverse side chains add considerably to the size of the core proteins and serve as binding sites for growth factors,cytokines,and extracellular matrix proteins.Syndecans are present as homodimers or multimers,and are often expressed in developmental and cell type-specific patterns.It is expressed highly in liver,kidney and lung.SDC4 localizes to the focal adhesions of adherent cells and binds to a range of extracellular ligands,including growth factors and extracellular-matrix proteins.Through its extracellular domain,syndecan-4 cooperates with adhesion molecules and binds matrix components relevant for cell migration.As a heparan sulfate proteoglycan,SDC4 works as a coreceptor for various growth factors.Syn4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization.SDC4 have an array of functions including regulating cell growth,differentiation,and adhesion. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验TSA Treatment of Mammalian Cells (PROT09)
towards the nuclear periphery and loss of HP1 proteins ensue after several divisions. Meanwhile, DNA methylation state and core centromeric markers are maintained. Subsequent defects in centromeric function arise in mitosis. Remarkably, removal of the drug rapidly
Purification of Human Multiprotein Complexes using OneSTrEP Technology (PROT41)
. Elution of the complexes by competition with D-biotin is efficient and can be done in a variety of buffer conditions allowing biochemical active complexes to be preserved. For more theoretical background and a protocol for purification of recombinant
strains. 1. Use C57BL/6 F1 mice to set up new breeding cages (see mouse breeding suggestions above). Most C57BL/6 F1 hybrids have good reproductive performance. We prefer (C57BL/6J X DBA/2J)F1 animals. Outbred CD-1 and ICR mice can be used
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