- ￥624 - 11520
- Solarbio
- P00554
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥11520.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥7200.0 |
| 规格： | 50ug | 产品价格： | ￥1872.0 |
| 规格： | 10ug | 产品价格： | ￥624.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Growth/differentiation factor 5;GDF-5;Bone morphogenetic protein 14;BMP-14;Cartilage-derived morphogenetic protein 1;CDMP-1;Lipopolysaccharide-associated protein 4;LAP-4;LPS-associated protein 4;Radotermin;CDMP1 |
| 中文名称 | Recombinant Human GDF-5/BMP-14 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Growth Differentiation Factor 5(GDF-5，BMP-14) is a member of the BMP family of TGFβ superfamily proteins.Human GDF-5，-6，and -7 are a defined subgroup of the BMP family.GDF-5 is synthesized as a homodimeric precursor protein consisting of a 354 amino acid (aa) Nterminal proregion and a 120 aa C-terminal mature peptide.Mature human GDF-5 shares 99% aa sequence identity with both mature mouse and rat GDF-5.GDF-5 signaling is mediated by formation of a heterodimeric complex consisting of a type 1 (BMPR-IB) and a type II (BMPR-IIor Activin RII) serine/threonine kinase receptor which results in the phosphorylation and activation of cytosolic Smad proteins (Smad1，5，and 8).GDF-5 is involved in multiple developmental processes including limb generation，cartilage development，joint formation，bone morphogenesis，cell survival，and neuritogenesis.Inhibition of GDF-5 expression or alteration of its signaling can facilitate the development of osteoarthritis. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM HCl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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P00554 Recombinant Human GDF-5/BMP-14 细胞因子/蛋白
￥624 - 11520
