- ￥1560 - 23040
- Solarbio
- P00222
- 北京
- 2025年07月25日
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- 详细信息
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥23040.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥16128.0 |
| 规格： | 50ug | 产品价格： | ￥4576.0 |
| 规格： | 10ug | 产品价格： | ￥1560.0 |
Recombinant Human Indoleamine 2,3-dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Gly403 is expressed with a 6His tag at the N-terminus.
| 基本信息 | |
| 基因名 | |
| 别名 | Indole 2;3-dioxygenase;Indoleamine 2;3-dioxygenase 1;IDO-1;IDO1;IDO;INDO |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 20mM Sodium Acetate, 150mM NaCl and 20% Glycerol, pH4.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Indoleamine 2，3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant，essential amino acid，l-tryptophan，along the kynurenine pathway.This protein is normally expressed in the dendritic cells，macrophages，microglia，eosinophils，fibroblasts，endothelial cells，and most tumor cells.IDO activity is associated with immunosuppression and immune attenuation.Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages.IDO also is a promising therapeutic target for the treatment of cancer，chronic viral infections，and other diseases characterized by pathological immune suppression. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/g(1 IEU/g)as determined by LAL test. |
| 单位 | 支 |
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P00222 Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO 细胞因子/蛋白
￥1560 - 23040
