P00218 Recombinant Human C-C

Recombinant Human C-C Motif Chemokine 2 is produced by our E.coli expression system and the target gene encoding Gln24-Thr99 is expressed.

基本信息
基因名
别名	C-C motif chemokine 2;HC11;Monocyte chemoattractant protein 1;Monocyte chemotactic and activating factor;MCAF;Monocyte chemotactic protein 1;MCP-1;Monocyte secretory protein JE;Small-inducible cytokine A2;CCL2
外观(性状)	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
纯度	≥95% as determined by reducing SDS-PAGE.
储存条件	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件	The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
背景说明	The chemokine (C-C motif) ligand 2 (CCL2)，also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2))，is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction.Its cognate receptor，CCR2，play a critical role in regulating nociceptive processes during neuropathic pain.Both CCL2 and CCR2 are implicated in induction of autoimmunity.CCL2 recruits monocytes，memory T cells，and dendritic cells to the sites of inflammation produced by either tissue injury or infection.Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.
来源	E.coli
溶剂	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素	Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.
单位	支