相关产品推荐更多 >

P01073 Recombinant Mouse S100 Calcium Binding Protein A15A/S100A15A 细胞因子/蛋白
¥988
P00948 Recombinant Human ALDH1A1/Aldehyde Dehydrogenase 1-A1 细胞因子/蛋白
¥988
P00675 Recombinant Mouse Fc gamma RI/CD64/FCGR1A 细胞因子/蛋白
¥780
P00631 Recombinant Human CD27 Ligand/TNFSF7/CD70 细胞因子/蛋白
¥741
P00430 Recombinant Human HTRA2/Serine protease HTRA2 细胞因子/蛋白
¥520
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2964.0 |
| 规格: | 10ug | 产品价格: | ¥468.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Mothers Against Decapentaplegic Homolog 4;MAD Homolog 4;Mothers Against DPP Homolog 4;Deletion Target in Pancreatic Carcinoma 4;SMAD Family Member 4;SMAD 4;Smad4;hSMAD4;SMAD4;DPC4;MADH4 |
| 中文名称 | Recombinant Human SMAD4/SMAD family member 4 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, pH8.0. |
| 纯度 | Greater than85% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family.SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain.It is the component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling.SMAD4 promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription.SMAD4 may act as a tumor suppressor.It positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.Mutations or deletions in SMAD4 have been shown to result in pancreatic cancer,juvenile polyposis syndrome,and hereditary hemorrhagic telangiectasia syndrome. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Mimic-Based RT-PCR Quantitation of Substance P mRNA in Human Mononuclear Phagocytes and Lymphocytes
Substance P (SP), the most extensively studied and most potent member of the tachykinin family, is a modulator in neuroimmunoregulation (1 –4 ). SP has been described as a peptide that is almost exclusively of neural origin
TRAF‐Mediated TNFR‐Family Signaling
, A.M., Dowd, A.D., Brush, A.D., Heldens, A.D., Schow, A.D., Goddard, A.D., Wood, W.I., Baker, K.P., Godowski, P.J., and Ashkenazi, A. 1999. Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse
Introduction of human 14-3-3 proteins
of their association with the G-box DNA/protein complex by a monoclonal antibody screening approach.GF14 proteins are homologous to the 14-3-3 family of mammalian proteins.Here we demonstrate that recombinant GF14 omega,one member of the Arabidopsis GF14 protein family
技术资料暂无技术资料 索取技术资料





