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- Solarbio
- P00406
- 北京
- 2025年07月25日
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- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥1092.0 |
| 规格： | 10ug | 产品价格： | ￥468.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Ubiquitin-Like Protein ISG15;Interferon-Induced 15 kDa Protein;Interferon-Induced 17 kDa Protein;IP17;Ubiquitin Cross-Reactive Protein;hUCRP;ISG15;G1P2;UCRP |
| 中文名称 | Recombinant Human ISG15/UCRP |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 100mM NaCl, pH 8.0. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta.Several functions have been ascribed to the encoded protein，including chemotactic activity towards neutrophils，direction of ligated target proteins to intermediate filaments，cell-to-cell signaling，and antiviral activity during viral infections.While conjugates of this protein have been found to be noncovalently attached to intermediate filaments，this protein is sometimes secreted.ISG15 becomes conjugated to a diverse set of proteins after IFN-alpha/beta stimulation or microbial challenge.The functions or biochemical consequences ISG15 conjugation to proteins are not yet known，but it appears that this modification does not target proteins for proteasomal degradation.ISG15 shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors.Upon interferon treatment，ISG15 can be detected in both free and conjugated forms，and is secreted from monocytes and lymphocytes where it can function as a cytokine.In the cell，ISG15 co-localizes with intermediate filaments and ISGylation may modulate the JAK-STAT pathway or certain aspects of neurological disease. |
| 来源 | E.coli |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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我们知道，PeproTech的所有细胞因子和蛋白均为冻干粉，这使得运输非常便捷，只要常温即可。而且，细胞因子和蛋白冻干粉非常稳定，在-20℃或-80℃条件下可保存数年。冻干粉在使用前需进行溶解，然后以液体形式加到培养体系或注射入动物体内。溶解步骤非常关键，因溶解不好会导致细胞因子或蛋白的失活，这也是很多用户在实际使用中经常遇到的问题。 那么，应该如何进行正确的溶解呢？ 下面我们以Recombinant Human IL-4 (重组人IL-4，产品编号：200-04)的说明书为例
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