P00394 Recombinant Human GFR a
lpha-1/GFRA1/GDNF family receptor alpha-1/RETL1/RET ligand 1/TRNR1 细胞因子/蛋白- ￥416 - 10560
- Solarbio
- P00394
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥10560.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥7392.0 |
| 规格： | 50ug | 产品价格： | ￥1248.0 |
| 规格： | 10ug | 产品价格： | ￥416.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | GFRα1;GDNF Family Receptor Alpha-1;GDNF Receptor Alpha-1;GDNFR-Alpha-1;GFR-Alpha-1;RET Ligand 1;TGF-Beta-Related Neurotrophic Factor Receptor 1;GFRA1;GDNFRA;RETL1;TRNR1 |
| 中文名称 | Recombinant Human GFR alpha-1/GFRA1/GDNF family receptor alpha-1/RETL1/RET ligand 1/TRNR1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Glial Cell Line-Derived Neurotrophic Factor Family Receptor α-1 (GDNFRα1) is a glycosylphosphatidylinositol (GPI) linked cell surface protein belonging to GDNF-family receptor α subtype which consists of at least four members.GFRα1and GFRα2 are the cognate co-receptor for the neurotrophic factor neurturin mediating the NRTN-induced autophosphorylation and activation of the RET tyrosine kinase receptor.Soluble GFRαs released enzymatically from the cell surface by phosphatidylinositol phospholipase C，as well as recombinantly produced soluble GFRα1，can also bind with high affinity to GDNF and trigger the activation of Ret tyrosine kinase.Human GFRα1 shares 93% amino acid identity with mouse GFRα1.The expression of the various GFRαs are differentially regulated in the central and peripheral nervous system，suggesting complementary roles for the GFRαs in mediating the activities of the GDNF family of neurotrophic factors. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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