薯蓣皂苷
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薯蓣皂苷

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  • ¥452
  • YOYOBIO
  • 上海
  • YJ-B21176-20mg
  • 2025年11月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      2-8℃

    • 保质期

      见包装

    • 英文名

      Dioscin

    • 库存

      大量现货

    • 供应商

      上海研谨生物

    • CAS号

      19057-60-4

    • 规格

      20mg

    薯蓣皂苷

    分析标准品,HPLC≥98%

    Dioscin

    CAS号:19057-60-4

    分子式:C45H72O16

    分子量:869.054

    MDLMFCD02094174

    别名:collettisideiii; polyphyllin III; Dioscin

    货号

    规格/参数/品牌

    价格

    货期

    YJ-B21176-20mg

    分析标准品,HPLC≥98%

    452.00

    现货

    YJ-B21176-1g

    分析标准品,HPLC≥98%

    3580.00

    现货

    JS27825-25mg

    ≥95% (HPLC)

    280.00

    现货

    JS27825-100mg

    ≥95% (HPLC)

    500.00

    现货

    JS27825-500mg

    ≥95% (HPLC)

    1200.00

    现货

    A10252-20mg

    分析标准品,含量93.7%,可溯源

    2100.00

    现货

     

    产品介绍

     Dioscin(CCRIS 4123; Collettiside III)是天然的植物来源的甾体皂苷,针对多种癌细胞有较好的抗癌活性。

    熔点:294-296 ℃

    比旋光度:D13 -115° (c = 0.373 in ethanol)

    外观:白色或微黄的结晶性粉末

    溶解性:DMSO  :  ≥  100  mg/mL  (115.07  mM)

    敏感性:易吸潮

    储存条件:2-8℃

    注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

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    图标文献和实验
    该产品被引用文献

    参考文献(46)

    46. [IF=6.1] Yunyun Zheng et al."Recognition of bioactive saponins from Polygonatum based on UPLC-QTOF/MS and molecular docking."TALANTA.2026 Jan;297:128485

    45. [IF=4.9] Wanyun Dang et al."Protective Effects of Dioscin and Diosgenin on Plateau Hyperuricemia by Attenuating Renal Inflammation via EPHX2."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Dec;25(24):13399

    44. [IF=5.7] Gaodan Liu et al."Novel Nanoliposomes Synergistically Modulated by Sitogluside and Dioscin: Stability, Bioavailability, and Capacity To Alleviate Hyperuricaemia."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;XXXX(XXX):XXX-XXX

    43. [IF=3.9] Qile Xia et al."Inhibitory effect and mechanism of purified saponin from Polygonatum cyrtonema Hua on human ovarian cancer cell A2780."FOOD AND CHEMICAL TOXICOLOGY.2025 Mar;:115368

    42. [IF=3.8] Zhang Chenxu et al."Integrating network pharmacology and experimental validation to decipher the pharmacological mechanism of DXXK in treating diabetic kidney injury."Scientific Reports.2024 Sep;14(1):1-15

    41. [IF=4.8] Chengfei Zhang et al."Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling."Drug Design Development and Therapy.

    40. [IF=6.208] Weipeng Wang et al."The Functional Characterization of DzCYP72A12-4 Related to Diosgenin Biosynthesis and Drought Adaptability in Dioscorea zingiberensis."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(9):8430

    39. [IF=3.614] Gaodan Liu et al."Extraction and identification of steroidal saponins from Polygonatum cyrtonema Hua using natural deep eutectic solvent-synergistic quartz sand assisted extraction method."JOURNAL OF SEPARATION SCIENCE.2023 Feb;:2200823

    38. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

    37. [IF=4.412] Feng Su et al."Study of Chemical Compositions and Anticancer Effects of Paris polyphylla var. Chinensis Leaves."MOLECULES. 2022 Jan;27(9):2724

    36. [IF=5.753] Jianghong Gao et al."Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.."Front Plant Sci. 2021 Dec;12:809579-809579

    35. [IF=2.998] Wang Zhijuan et al.Preparation of dioscin from Trigonella foenum-graecum by foam separation–preparative high-performance liquid chromatography.European Food Research And Technology.2021 Nov 24

    34. [IF=7.658] Yu-Xi Liu et al.Inhibition of Src/STAT3 signaling-mediated angiogenesis is involved in the anti-melanoma effects of dioscin.Pharmacol Res. 2022 Jan;175:105983

    33. [IF=2.055] Jieru Han et al."Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study."J Nat Med-Tokyo. 2021 Jan;75(1):37-47

    32. [IF=2.1] Yuyan Zhang et al."Tanshinone I and simvastatin inhibit melanoma tumour cell growth by regulating poly (ADP ribose) polymerase 1 expression."Mol Med Rep. 2021 Jan;23(1):1-1

    31. [IF=2.289] Zhou  Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150

    30. [IF=2.311] Yu‑Xi  Liu et al."Inhibiting the Src/STAT3 signaling pathway contributes to the anti‑melanoma mechanisms of dioscin."Oncol Lett. 2020 Mar;19(3):2508-2514

    29. [IF=3.412] Shun Zhou et al."Antiparasitic Efficacy of Herbal Extracts and Active Compound Against Gyrodactylus kobayashii in Carassius auratus."Front Vet Sci. 2021; 8: 665072

    28. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992

    27. [IF=4.466] Yao Tan et al."Multiomics Integrative Analysis for Discovering the Potential Mechanism of Dioscin against Hyperuricemia Mice."J Proteome Res. 2021;20(1):645–660

    26. [IF=4.952] Qun Yu et al."Enhancing the antityrosinase activity of saponins and polyphenols from Asparagus by hot air coupled with microwave treatments."Lwt Food Sci Technol. 2020 Apr;124:109174

    25. [IF=5.645] Lixiu Hou et al."Geographical variations in fatty acid and steroid saponin biosynthesis in Dioscorea zingiberensis rhizomes."Ind Crop Prod. 2021 Oct;170:113779

    24. [IF=5.923] Lixiu Hou et al."Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis."Int J Mol Sci. 2021 Jan;22(20):10953

    23. [IF=2.998] Lei  Lei et al."Preparation of diosgenin from Dioscorea zingiberensis C. H. Wright by stepwise biocatalysis-foam separation-preparative high-performance liquid chromatography (P-HPLC)."Eur Food Res Technol. 2018 Aug;244(8):1447-1452

    22. [IF=3.998] Yang  Rui et al."Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism."Sci Rep-Uk. 2017 Jan;7(1):1-13

    21. [IF=4.759] Mengshun Liu et al."Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides."J Chromatogr A. 2014 Nov;1368:116

    20.  Liu, Mengshun, et al. "Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides." Journal of Chromatography A 1368 (2014): 116-124.https:##

    19.  Wang, Peng, et al. "Ionic liquid-based ultrasonic/microwave-assisted extraction of steroidal saponins from Dioscorea zingiberensis CH Wright." Tropical Journal of Pharmaceutical Research 13.8 (2014): 1339-1345.https:##doi.org/10.4314/tjpr.v13i8.20

    18.  Tan, Yao, et al. "Multiomics integrative analysis for discovering the potential mechanism of dioscin against hyperuricemia mice." Journal of Proteome Research 20.1 (2020): 645-660.https:##doi.org/10.1021/acs.jproteome.0c00584

    17.  马境谦,崔乃菠,余河水,李正,刘二伟,别松涛.基于4种皂苷的定量分析评价干燥方式对菊叶薯蓣有效成分的影响[J].中南药学,2021,19(03):413-418.

    16.  张剑,谭健聪,杨钰蓉,张博,韩禄,刘春叶.响应曲面法优化蒺藜中黄酮和皂苷的提取工艺[J].化工科技,2020,28(06):6-12.

    15.  梁玉琼,黄庆,梁天坚,汪磊,覃日宏,盘涌,滕丽娟,罗彩神.薯蓣皂苷对肝癌细胞Bel-7402和正常人肝细胞LO2增殖和凋亡的影响[J].中国比较医学杂志,2021,31(03):30-35.

    14.  贺子倩, 彭青, 蔡道琳,. 狭叶荨麻醇提物的体外抗氧化及抗炎活性[J]. 现代食品科技, 2018, v.34;No.228(08):42-49+135.

    13.  朱昀, 王未, 李倩,. 百合珠芽与鳞茎营养成分及活性成分研究[J]. 生物技术进展, 2016, 006(005):336-340.

    12.  宋发军 刘佳 张鹏 余晓东 吴瑞云. 重楼地上部分薯蓣皂苷含量的HPLC分析[J]. 中南民族大学学报:自然科学版, 2015(34):36-38.

    11.  张亚欣, 王宇光, 马增春,. 薯蓣皂苷致肝毒性及其机制的初步研究[J]. 中国中药杂志, 2015(14):2748-2752.

    10.  李倩,巴寅颖,刘璐,申立峰,孙仁弟,张媛媛,孔静,路东波,王梦林,石任兵.百合指标性成分含量测定及其特征图谱质量表征关联分析研究[J].环球中医药,2018,11(04):513-519.

    9.  黄涵, 王宇卿. 瓜蒌薤白半夏胶囊提取工艺的优化[J]. 中成药, 2019, 41(02):182-185.

    8.  孙鹏, 尹海波, 姚佳. 基于连作障碍条件下穿山龙皂苷类活性成分的含量变化[J]. 实用药物与临床, 2016(3):339-342,4.

    7.  姚佳, 尹海波, 赵容,. 基于连作障碍条件下穿山龙无机元素吸收规律及总皂苷含量分析[J]. 中国实验方剂学杂志, 2015, v.21(24):69-72.

    6.  王仕宝  苏莹  李会宁 等. 响应面法优化重楼药材中甾体皂苷的回流提取工艺研究[J]. 陕西农业科学  2019  065(001):46-52.

    5.  高行恩 贾永康 王洪新.不同烹饪工艺对淮山药功能性成分的影响[J].食品研究与开发 2015 36(20):9-12.

    4.  白桥 刘珍珍 徐皓.不同产地野生黄姜中薯蓣皂苷含量的比较[J].中国药房 2019 30(05):681-684.

    3.  贾晓晴  尹海波  陶玲 等. 不同产地穿山龙活性成分与环境因子相关性研究[J]. 辽宁中医杂志  2017  04(v.44;No.479):154-158.

    2.  王仕宝  蔡艳妮  贾慧梅 等. HPLC法测定不同来源重楼药材中7种甾体皂苷的含量[J]. 西北药学杂志  2017  32(002):133-138.

    1.  杨亚利  刘佳  张鹏 等. 4种重楼不同部位薯蓣皂苷及皂苷元含量的分析[J]. 时珍国医国药  2016(5):1035-1038.

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