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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Dioscin
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
19057-60-4
- 规格:
20mg
薯蓣皂苷
分析标准品,HPLC≥98%
Dioscin
CAS号:19057-60-4
分子式:C45H72O16
分子量:869.054
MDL:MFCD02094174
别名:collettisideiii; polyphyllin III; Dioscin
|
货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B21176-20mg |
分析标准品,HPLC≥98% |
¥452.00 |
现货 |
|
YJ-B21176-1g |
分析标准品,HPLC≥98% |
¥3580.00 |
现货 |
|
JS27825-25mg |
≥95% (HPLC) |
¥280.00 |
现货 |
|
JS27825-100mg |
≥95% (HPLC) |
¥500.00 |
现货 |
|
JS27825-500mg |
≥95% (HPLC) |
¥1200.00 |
现货 |
|
A10252-20mg |
分析标准品,含量93.7%,可溯源 |
¥2100.00 |
现货 |
产品介绍
Dioscin(CCRIS 4123; Collettiside III)是天然的植物来源的甾体皂苷,针对多种癌细胞有较好的抗癌活性。
熔点:294-296 ℃
比旋光度:D13 -115° (c = 0.373 in ethanol)
外观:白色或微黄的结晶性粉末
溶解性:DMSO : ≥ 100 mg/mL (115.07 mM)
敏感性:易吸潮
储存条件:2-8℃
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文献和实验参考文献(46篇)
46. [IF=6.1] Yunyun Zheng et al."Recognition of bioactive saponins from Polygonatum based on UPLC-QTOF/MS and molecular docking."TALANTA.2026 Jan;297:128485
45. [IF=4.9] Wanyun Dang et al."Protective Effects of Dioscin and Diosgenin on Plateau Hyperuricemia by Attenuating Renal Inflammation via EPHX2."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Dec;25(24):13399
44. [IF=5.7] Gaodan Liu et al."Novel Nanoliposomes Synergistically Modulated by Sitogluside and Dioscin: Stability, Bioavailability, and Capacity To Alleviate Hyperuricaemia."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;XXXX(XXX):XXX-XXX
43. [IF=3.9] Qile Xia et al."Inhibitory effect and mechanism of purified saponin from Polygonatum cyrtonema Hua on human ovarian cancer cell A2780."FOOD AND CHEMICAL TOXICOLOGY.2025 Mar;:115368
42. [IF=3.8] Zhang Chenxu et al."Integrating network pharmacology and experimental validation to decipher the pharmacological mechanism of DXXK in treating diabetic kidney injury."Scientific Reports.2024 Sep;14(1):1-15
41. [IF=4.8] Chengfei Zhang et al."Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling."Drug Design Development and Therapy.
40. [IF=6.208] Weipeng Wang et al."The Functional Characterization of DzCYP72A12-4 Related to Diosgenin Biosynthesis and Drought Adaptability in Dioscorea zingiberensis."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(9):8430
39. [IF=3.614] Gaodan Liu et al."Extraction and identification of steroidal saponins from Polygonatum cyrtonema Hua using natural deep eutectic solvent-synergistic quartz sand assisted extraction method."JOURNAL OF SEPARATION SCIENCE.2023 Feb;:2200823
38. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199
37. [IF=4.412] Feng Su et al."Study of Chemical Compositions and Anticancer Effects of Paris polyphylla var. Chinensis Leaves."MOLECULES. 2022 Jan;27(9):2724
36. [IF=5.753] Jianghong Gao et al."Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.."Front Plant Sci. 2021 Dec;12:809579-809579
35. [IF=2.998] Wang Zhijuan et al.Preparation of dioscin from Trigonella foenum-graecum by foam separation–preparative high-performance liquid chromatography.European Food Research And Technology.2021 Nov 24
34. [IF=7.658] Yu-Xi Liu et al.Inhibition of Src/STAT3 signaling-mediated angiogenesis is involved in the anti-melanoma effects of dioscin.Pharmacol Res. 2022 Jan;175:105983
33. [IF=2.055] Jieru Han et al."Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study."J Nat Med-Tokyo. 2021 Jan;75(1):37-47
32. [IF=2.1] Yuyan Zhang et al."Tanshinone I and simvastatin inhibit melanoma tumour cell growth by regulating poly (ADP ribose) polymerase 1 expression."Mol Med Rep. 2021 Jan;23(1):1-1
31. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150
30. [IF=2.311] Yu‑Xi Liu et al."Inhibiting the Src/STAT3 signaling pathway contributes to the anti‑melanoma mechanisms of dioscin."Oncol Lett. 2020 Mar;19(3):2508-2514
29. [IF=3.412] Shun Zhou et al."Antiparasitic Efficacy of Herbal Extracts and Active Compound Against Gyrodactylus kobayashii in Carassius auratus."Front Vet Sci. 2021; 8: 665072
28. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992
27. [IF=4.466] Yao Tan et al."Multiomics Integrative Analysis for Discovering the Potential Mechanism of Dioscin against Hyperuricemia Mice."J Proteome Res. 2021;20(1):645–660
26. [IF=4.952] Qun Yu et al."Enhancing the antityrosinase activity of saponins and polyphenols from Asparagus by hot air coupled with microwave treatments."Lwt Food Sci Technol. 2020 Apr;124:109174
25. [IF=5.645] Lixiu Hou et al."Geographical variations in fatty acid and steroid saponin biosynthesis in Dioscorea zingiberensis rhizomes."Ind Crop Prod. 2021 Oct;170:113779
24. [IF=5.923] Lixiu Hou et al."Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis."Int J Mol Sci. 2021 Jan;22(20):10953
23. [IF=2.998] Lei Lei et al."Preparation of diosgenin from Dioscorea zingiberensis C. H. Wright by stepwise biocatalysis-foam separation-preparative high-performance liquid chromatography (P-HPLC)."Eur Food Res Technol. 2018 Aug;244(8):1447-1452
22. [IF=3.998] Yang Rui et al."Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism."Sci Rep-Uk. 2017 Jan;7(1):1-13
21. [IF=4.759] Mengshun Liu et al."Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides."J Chromatogr A. 2014 Nov;1368:116
20. Liu, Mengshun, et al. "Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides." Journal of Chromatography A 1368 (2014): 116-124.https:##
19. Wang, Peng, et al. "Ionic liquid-based ultrasonic/microwave-assisted extraction of steroidal saponins from Dioscorea zingiberensis CH Wright." Tropical Journal of Pharmaceutical Research 13.8 (2014): 1339-1345.https:##doi.org/10.4314/tjpr.v13i8.20
18. Tan, Yao, et al. "Multiomics integrative analysis for discovering the potential mechanism of dioscin against hyperuricemia mice." Journal of Proteome Research 20.1 (2020): 645-660.https:##doi.org/10.1021/acs.jproteome.0c00584
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1. 杨亚利 刘佳 张鹏 等. 4种重楼不同部位薯蓣皂苷及皂苷元含量的分析[J]. 时珍国医国药 2016(5):1035-1038.
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