- ￥1668
- abinScience
- China
- BB908013
- 2026年03月03日
- ELISA
- Human
- Bovine
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human
- 亚型：
Fab - G1 - kappa
- 形态：
Liquid
- 保存条件：
0.01M PBS pH 7.4
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Bovine
- 保质期：
1 year
- 抗原来源：
Human
- 目录编号：
BB908013
- 级别：
科研级别
- 库存：
999
- 供应商：
abinScience
- 宿主：
Human
- 应用范围：
ELISA
- 浓度：
1mg/mL
- 靶点：
Beta-arrestin-1, Arrestin beta-1, Arrestin-2, ARRB1, Beta-arrestin-2, Arrestin beta-2, Arrestin-3, ARRB2
- 抗体英文名：
Anti-Bovine ARRB1/ARRB2 Antibody (Fab7)
- 抗体名：
Anti-Bovine ARRB1/ARRB2 Antibody (Fab7)
- 规格：
100ul
| Product name | Anti-Bovine ARRB1/ARRB2 Antibody (Fab7) |
|---|---|
| Catalog No. | BB908013 |
| Host species | Human |
| Species reactivity | Bovine |
| Immunogen | / |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | Fab - G1 - kappa |
| Applications | ELISA |
| Target | Beta-arrestin-1, Arrestin beta-1, Arrestin-2, ARRB1, Beta-arrestin-2, Arrestin beta-2, Arrestin-3, ARRB2 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | / |
| Accession | P17870, P32120 |
| Alternative Names | / |
| Clone ID | Fab7 |
| Species | / |
| Product Usage Information | / |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for abinScience's product research and development.
Product categories and application fields.
Main products.
10000+ high-activity proteins.
15000+ antibody series products:
Classic monoclonal antibody.
Monoclonal antibody
Internal control antibody, labeled antibody.
High-quality phosphorylation antibodies.
Highly specific nanobodies and small molecule antibodies.
Functional antibodies in vivo.
Low-background flow cytometry antibodies.
DNA/RNA antibodies and PEG antibodies.
1000+ reagent kit series products.
Large-scale packaging customization services: We offer personalized antibody design, protein production, molecular optimization, and experimental development services.
Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
Neuroscience research: Supporting research on neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验• ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia., PMID:24988431
• Opposing functions of β-arrestin 1 and 2 in Parkinson's disease via microglia inflammation and Nprl3., PMID:33686256
• β-Arrestin 2 is a mediator of GnRH-(1-5) signaling in immortalized GnRH neurons., PMID:24140715
• β-Arrestin-1 mediates thyrotropin-enhanced osteoblast differentiation., PMID:24723693
• beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking., PMID:11171997
• Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation., PMID:21855149
• Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes., PMID:7695743
• Ultrastructural localization of beta-arrestin-1 and -2 in rat lumbar spinal cord., PMID:10464360
• β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas: role in the regulation of response to somatostatin analogue treatment in patients with acromegaly., PMID:24169548
、结果1、MTT法测定结果为了检验嵌合抗CD20Fab’片段对Raji细胞，的生长抑制作用，以PBS为阴性对照，用MTT法测定Fab’片段对Raji细胞生长的影响，其结果显示，Fab’片段对Raji细胞具有抑制作用，其抑制作用具有明显的剂量依赖性，其半数抑制量为（24.2±7.8） µg/ml。表1嵌合抗体CD20 Fab’片段对Raji细胞的生长抑制率Tab 1 The inhibition rate of Raji cells by the anti-CD20 chimeric fragment Fab
可能与其他物种发生交叉反应， 除非特异性的经过交叉反应物种的吸附处理。在抗体描述中，经过其他物种的吸附处理的抗体标有“ (min X …Sr Prot) ”字样 。 Anti-IgG (H+L) 这类抗体和 IgG 分子的重链和轻链都可以反应，比如，和 IgG 分子的 Fc ， F(ab ’)2/Fab 部分。 Anti-IgG (H+L) 抗体也可以和其他的免疫球蛋白家族（ IgM ， IgA ，IgD,IgE ）和亚家族反应，因为所有的免疫球蛋白都有相同的轻链（或者 κ 链
相关专题单克隆抗体 单克隆抗体问世以来，在临床诊断、治疗与预防等方面发挥了巨大的作用。但是常用的鼠源单克隆抗 体具有较强的免疫原性，在临床反复应用中会引起人抗鼠抗体（ｈｕｍａｎ ａｎｔｉ －ｍｏｕｓｅ ａｎｔｉｂｏｄｙ，ＨＡＭＡ）反应， 导致半衰期缩短，治疗效果减弱。鼠源抗体人源化是指利用ＤＮＡ 重组技术和蛋白质工程技术，对抗体基 因进行重组，在保留鼠源抗体对抗原有效结合部位的同时，最大限度地降低非结合部位的鼠源性。这种通 过重组基因所表达
技术资料暂无技术资料 索取技术资料
