α-Cyperone

一种具有多种生物活性的倍半萜类化合物；在RAW 264.7细胞中抑制LPS诱导的p65核转位以及PGE₂和IL-6的产生；在15µM和30µM浓度下减少过氧化氢诱导的SH-SY5Y细胞中活性氧（ROS）的产生和细胞凋亡；在感染的HepG2.2.15细胞中降低乙型肝炎表面抗原（HBsAg）的产生（IC₅₀=274.7µM）。A sesquiterpenoid with diverse biological activities; inhibits LPS-induced nuclear translocation of p65, as well as LPS-induced production of PGE2 and IL-6, in RAW 264.7 cells; reduces hydrogen peroxide-induced production of ROS and apoptosis in SH-SY5Y cells at 15 and 30 µM; reduces the production of HBsAG in infected HepG2.2.15 cells (IC50 = 274.7 µM).分子式C15H22O分子量218.3C[C@]12C(C[C@@H](CC1)C(C)=C)=C(C(CC2)=O)C