Sunset Yellow FCF

偶氮染料；abs=480nm；在浓度为250µg/ml时，可降低LPS诱导的小鼠分离脾细胞增殖，并抑制同种异体混合淋巴细胞反应中小鼠分离脾细胞的增殖；在剂量为0.325mg/kg时，可诱发小鼠体细胞和生殖细胞的染色体畸变以及精子的形态异常；在剂量高达2,000mg/kg时，在小鼠微核肠道试验中不产生遗传毒性。An azo dye; abs = 480 nm; reduces LPS-induced proliferation of isolated mouse splenocytes, as well as inhibits proliferation of isolated mouse splenocytes in an allogenic mixed lymphocyte reaction at 250 µg/ml; induces chromosomal aberrations in somatic and germ cells and morphological abnormalities in sperm in mice at 0.325 mg/kg; not genotoxic in a micronucleus gut assay in mice at doses up to 2,000 mg/kg.分子式C16H10N2O7S2 • 2Na分子量452.4O=S([O-])(C1=CC=C(C=C1)N=NC2=C(C=CC3=CC(S(=O)([O-])=O)=CC=C32)O)=O.[Na+].[Na+]