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产品编号:KMH343
产品名称:Recombinant Human CD160 Protein, C-His tag
中文名称: 重组人CD160蛋白
产品描述:产品描述:Recombinant Human CD160 Protein ( KMP-H1601) is produced in HEK293 Cells and the target gene encodes the Gln25-Ser162 mature peptide with a C-terminal 6×His tag fusion.
产品别称:CD160抗原, NK1, BY55, NK28, CD160 molecule
分子名称:CD160
预测分子量:22 kDa
物种:Human
宿主:HEK293 Cells
规格:20ug, 50ug, 100ug, 200ug, 1mg
纯化方式:Affinity Purification
纯度:≥95%
内毒素水平:<1.0 EU/ug determined by the LAL method
缓冲体系:PBS
Uniport:O95971
产品简介:CD160 (KMH343) 是自然杀伤细胞中的一个标志物,参与免疫细胞的激活与调节。
产品背景:CD160 antigen is a cell membrane protein which contains one Ig-likeV-type(immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
保存条件:Store the product under sterile conditions after opening at -80℃ for 12 months. Store the lyophilized powder at -20℃. Avoid repeated freeze-thaw cycles.
运输条件:This product is shipped on ice packs or dry ice.
说明:This product is for research use only.
常见问题:问:如何储存293F细胞中表达的蛋白? 答: 蛋白可以在-80°C下储存以便长期保存。应分装并避免冻融循环,以保持蛋白的稳定性。 问:如何提高293F细胞中的蛋白表达效率? 答: 可以通过优化质粒设计、使用高效转染试剂、优化细胞培养条件以及使用蛋白折叠伴侣或密码子优化来提高蛋白表达效率。
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文献和实验Primer Premier: Program for Design of Degenerate Primers from a Protein Sequence
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Chromatin Interaction Analysis Using Paired‐End Tag Sequencing
Analysis using Paired?End Tag sequencing (ChIA?PET) is a technique developed for large?scale, de novo analysis of higher?order chromatin structures. Cells are treated with formaldehyde to cross?link chromatin interactions, DNA segments bound by protein
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