Benzyl 4-Oxo-2-azetidinecarbox

Analysis of Urinary 8-oxo-7,8-dihydro-2-deoxyguanosine by Liquid ChromatographyTandem Mass Spectrometry

roles of DNA oxidation in various disease states and population or inter-individual differences in antioxidant defence and DNA repair. The analysis of urine, or indeed any extracellular matrix, for 8-oxo-7,8-dihydro-2ʹ-deoxyguanosine (8-oxodG), using

Measurement of 8-Oxo-deoxyguanosine in Lymphocytes, Cultured Cells, and Tissue Samples by HPLC with Electrochemical Detection

and hydrolysis of DNA, and derivatization of the bases for analysis. HPLC, normally applied to measurement of the nucleoside, 8-oxo-deoxyguanosine (8-oxo-dG), has generally given values below those obtained with GC-MS; but with HPLC, too, oxidation artefacts

Non-invasive Assessment of Oxidatively Damaged DNA: Liquid Chromatography-Tandem Mass Spectrometry Analysis of Urinary 8-Oxo-7,8-Dihydro-2-Deoxyguanos

to the genome is by the analysis of urine for 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), using chromatographic techniques or immunoassay procedures. The provenance of extracellular 8-oxodG remains a subject for debate