6-(1H-imidazol-1-yl)pyridine-3

Release of DNA Oligonucleotides and Their Conjugates from Controlled‐Pore Glass Under Thermolytic Conditions

before oxidation, but after sulfurization. BP , thymin‐1‐yl, N 4 ‐benzoylcytosin‐1‐yl, N 6 ‐benzoyladenin‐9‐yl, or N 2 ‐isobutyrylguanin‐9‐yl; Cap A, acetic anhydride/pyridine/THF; Cap B, 10% 1‐methylimidazole in THF; CPG, 500 Å long‐chain alkylamine controlled

Convenient and Efficient Approach to the Permanent or Reversible Conjugation of RNA and DNA Sequences with Functional Groups

) 0.25 M 5‐Benzylthio‐1H ‐tetrazole (Glen Research) Cap A solution: acetic anhydride in tetrahydrofuran/pyridine (Glen Research

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

for the etherification at the O 6 ?position of silyl?protected inosine, guanosine, and 2??deoxyguanosine is described. Typically, a THF solution of the silylated nucleoside is treated with 1H ?benzotriazol?1?yloxy?tris(dimethylamino)phosphonium hexafluorophosphate (BOP