5-OXO-1-(4-PYRIDINYLMETHYL)-3-

Determination of Acyl Homoserine Lactone and Tetramic Acid Concentrations in Biological Samples

for the detection of these QS signals may provide insights into the pathogenicity and survival of P. aeruginosa . In this chapter, we present a method for the extraction and quantitation of the P. aeruginosa QS signal N -3-oxo-dodecanoyl-homoserine lactone

Biotinylation of a Propargylated Cyclic (3′‐5′) Diguanylic Acid and of Its Mono‐6‐Thioated Analog Under “Click” Conditions

with the propargylated c?di?GMP diester under click conditions provides the biotinylated c?di?GMP conjugate in an isolated yield of 62%. Replacement of the 6?oxo function of N 2 ?isobutyryl?5??O ?(4,4??dimethoxytrityl)?3??O ?levulinyl?2??O ?(propargyl)guanosine with a 2

Expression and Purification of CRABPs from E. coli

Nuclear-retinoid receptors provide a mechanism of retinoid action, but most likely where expressed, the cytosolic cellular retinoic acid-binding proteins (CRABPs) also affect the ability of retinoids to initiate biological signals