Hydroxy Linoleins

羟基亚麻酸是132种可能的单羟基、二羟基和三羟基化合物异构体的混合物，由三亚油酸甘油酯的自氧化和随后的氢过氧化物还原而产生。含有亚油酸的甘油三酯（即三亚油酸甘油酯）在体内的自氧化可导致氢过氧化物的形成，然后氢过氧化物可被过氧化物酶还原以产生羟基亚麻酸。由于与前体氢过氧化物相比，羟基亚麻酸具有固有的稳定性，因此是体内甘油三酯脂质过氧化的潜在标志。Hydroxy linoleins are a mixture of 132 possible isomers of mono-, di-, and tri-hydroxy compounds produced by the autoxidation of trilinolein and subsequent reduction of the hydroperoxides. Autoxidation of linoleic acid containing triglycerides (i.e., trilinolein) in vivo could result in the formation of hydroperoxides, which could then be reduced by peroxidases to produce hydroxy linoleins. Due to their inherent stability compared to the precursor hydroperoxides, hydroxy linoleins are potential markers of triglyceride lipid peroxidation in vivo.分子式分子量CCCCC/C=C\C=C/C(O)CCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCC/C=C\C=C/C(O)CCCCC)OC(=O)CCCCCCC/C=C\C=C/C(O)CCCCC