- ￥2860
- LSM Bio
- 进口
- PAab09442
- 2025年07月13日
- ELISA,WB,IF
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
vacuolar protein sorting 41 homolog (S. cerevisiae)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
O95498
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
vacuolar protein sorting 41 homolog (S. cerevisiae)
- 抗体英文名：
anti-VPS41 antibody,VPS41 antibody
- 抗体名：
anti-VPS41 抗体,VPS41 抗体
- 规格：
100μl
VPS41抗体| VPS41 antibody
货号 PAab09442
蛋白别名 HVPS41 antibody, hVps41p antibody, HVSP41 antibody, S53 antibody, VPS41
蛋白介绍
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE- mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes (PubMed:23351085). Involved in homotypic vesicle fusions between late endosomes and in heterotypic fusions between late endosomes and lysosomes implicated in degradation of endocytosed cargo (PubMed:9159129, PubMed:23167963, PubMed:25445562, PubMed:25908847). Required for fusion of autophagosomes with lysosomes (PubMed:25783203). May link the HOPS complex to endosomal Rab7 via its association with RILP and to lysosomal membranes via its association with ARL8B, suggesting that these interactions may bring the compartments to close proximity for fusion (PubMed:25445562, PubMed:25908847). Involved in the direct trans-Golgi network to late endosomes transport of lysosomal membrane proteins independently of HOPS (PubMed:23322049). Involved in sorting to the regulated secretory pathway presumably implicating the AP-3 adaptor complex (By similarity). May play a role in HOPS-independent function in the regulated secretory pathway (PubMed:24210660).
产品描述
anti-VPS41 antibody is a Rabbit Polyclonal antibody againstVPS41..
建议稀释比例
WB :1:200-1:1000;IF:1：10-1：100
IHC
Western blot
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09442(VPS41 antibody) at dilution of 1:400(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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