- ￥2262
- LSM Bio
- 进口
- PAab08556
- 2025年07月15日
- ELISA,WB,IP
- E. coli - derived recombinant protein
- Human, Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
transcription factor 7-like 2 (T-cell specific, HMG-box)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
transcription factor 7-like 2 (T-cell specific, HMG-box)
- 抗体英文名：
anti-TCF7L2 antibody,TCF7L2 antibody
- 抗体名：
anti-TCF7L2 抗体,TCF7L2 抗体
- 规格：
100μg
TCF7L2抗体| TCF7L2 antibody
货号 PAab08556
蛋白别名 TCF4
蛋白介绍
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
产品描述
anti-TCF7L2 antibody is a Rabbit Polyclonal antibody againstTCF7L2..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验浅析染色质免疫沉淀（ChIP）技术在 DNA 与蛋白质相互作用研究中的重要性
-9. [25] Hatzis, P., et al., Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol, 2008. 28(8): p. 2732-44. [26] Seo, S., et al., Neurogenin and NeuroD direct transcriptional targets and their regulatory
浅析染色质免疫沉淀（ChIP）技术在DNA与蛋白质相互作用研究中的重要性
histone marks to promote androgen-receptor-dependent transcription. Nature , 2005. 437(7057): p. 436-9. 25. Hatzis, P., et al., Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol , 2008
12, TCF3, TCF7, TCF7L1, TCF7L2, TCF8, TGFB2, TGFBR3, TIAL1, TLX1, TM4SF2, TNFRSF17, TNFRSF8, TNK1, TOP1, TXK, TYMS, VAV2, VHL, WEE1, WT1, YWHAQ, ZAP70, ZNF145, ZNF42, ZNF593, ZNFN1A1. 请勿重复发贴！
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