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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
transcription factor 7-like 2 (T-cell specific, HMG-box)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
transcription factor 7-like 2 (T-cell specific, HMG-box)
- 抗体英文名:
anti-TCF7L2 antibody,TCF7L2 antibody
- 抗体名:
anti-TCF7L2 抗体,TCF7L2 抗体
- 规格:
100μg
TCF7L2抗体| TCF7L2 antibody
货号 PAab08556
蛋白别名 TCF4
蛋白介绍
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
产品描述
anti-TCF7L2 antibody is a Rabbit Polyclonal antibody againstTCF7L2..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验
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